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1.
Telemed J E Health ; 29(12): 1781-1791, 2023 12.
Artigo em Inglês | MEDLINE | ID: mdl-37092975

RESUMO

Introduction: To examine the use of telehealth for delivery of health care in persons with sickle cell disease in a resource-constrained country during the COVID-19 pandemic. Methods: This study was a retrospective review of patient encounters at the Sickle Cell Unit (SCU), Jamaica during a 3-year period, March 10, 2019 to March 9, 2022 and a comparison of endpoints between 1 year before and 2 years during the pandemic. Primary endpoints of registration numbers, day-care admissions, and study visits were obtained from logbooks and the electronic medical records. Additional endpoints included well visits, hydroxyurea (HU) visits, and bone pain crisis. Results: Patients registered at the clinic on 17,295 occasions, with 7,820 in the pre-pandemic year decreasing by 43.8% and 35% in the 2 subsequent pandemic years. Overall, study visits increased by 4.9% and 1.3% in the pandemic years. They increased in adults by 13.1% and 8.9% but fell by 3.2% and 6.2% in children. Fewer people were seen in the pandemic years, with children showing a 20.7% decline in numbers. Tele-visits accounted for 31.4% of all study visits during the pandemic years and increased by 23.6% between the pandemic years. There were more well-visits and HU visits, but fewer pain visits and day-care admissions in the pandemic years. Conclusions: The SCU maintained health care delivery for a high-risk population during the pandemic, with tele-visits mitigating the short-fall from in-person visits. Tele-visits may be more acceptable to adults with a chronic illness and may be a suitable alternative for delivering health care.


Assuntos
Anemia Falciforme , COVID-19 , Telemedicina , Adulto , Criança , Humanos , Pandemias , COVID-19/epidemiologia , Instituições de Assistência Ambulatorial , Anemia Falciforme/epidemiologia , Anemia Falciforme/terapia , Hidroxiureia , Dor
2.
J Gen Intern Med ; 36(10): 2929-2934, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-33547572

RESUMO

BACKGROUND: Internal medicine (IM) residency graduates consistently report being less prepared for outpatient practice than inpatient medicine. Although an initial study suggested interns arriving for IM residency reported low levels of preparedness for continuity clinic, the impact of education and experience during the undergraduate medical education to graduate medical education transition on ambulatory training is unclear. OBJECTIVE: To describe end of medical school primary care exposure among entering IM interns and its association with self-assessed preparedness for residency continuity clinic. DESIGN: Cross-sectional survey of 161 entering IM interns in 2019. PARTICIPANTS: Entering interns at four geographically diverse IM residency programs (University of Chicago, University of North Carolina, University of Pennsylvania, and University of Washington), representing 81 US medical schools. RESULTS: A total of 139 interns (86%) responded to the survey. Surveyed interns reported a median of zero days of general internal medicine (GIM) clinic (interquartile range [IQR]: 0-20 days) and 2.5 days of multispecialty adult primary care (IQR: 0-26.5 days) during fourth year of medical school. The median last exposure to primary care was 13 months prior to internship (IQR: 7-18 months). Interns who rated themselves as prepared for primary care clinic reported a median of twenty more multispecialty adult primary care days (20 vs. 0 days; p < 0.01) and fourteen more GIM clinic days (14 vs. 0 days; p < 0.01) than their unprepared counterparts. The experiences were also more recent, with six fewer months between their last multispecialty adult primary care exposure and the start of internship (9 vs. 15 months; p < 0.01). CONCLUSIONS: The majority of incoming IM interns had no primary care training during the fourth year of medical school. At the start of residency, IM interns who felt more prepared for their primary care clinic reported more recent and more numerous primary care experiences.


Assuntos
Internato e Residência , Adulto , Instituições de Assistência Ambulatorial , Competência Clínica , Estudos Transversais , Educação de Pós-Graduação em Medicina , Humanos , Atenção Primária à Saúde
3.
Health Res Policy Syst ; 19(1): 33, 2021 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-33691733

RESUMO

BACKGROUND: Understanding why research is conducted may help address the under-utilisation of research. This study examined the reasons for childhood obesity prevention knowledge production in New South Wales (NSW), Australia, and the factors influencing research choices from the perspective of the researchers and health policy agencies contributing to the research. METHODS: A literature search of SCOPUS and ISI Web of Knowledge (affiliation and key word searches) was conducted to compile a database of NSW childhood obesity research outputs, published between 2000 and 2015 (n = 543). Descriptive statistics were used to quantify outputs by research type, differentiating measurement, descriptive, and intervention research, systematic reviews and other publications. Interviews were conducted with a sample of researchers drawn from the database (n = 13) and decision makers from health policy agencies who funded and contributed to childhood obesity research in NSW (n = 15). Researcher interviews examined views about societal impacts, why and under what circumstances the research was conducted. Decision-maker interviews examined policy agency research investment and how research was used in decision making. Content analysis and a thematic approach was used to analyse the interview transcripts. RESULTS: The research in this case was conducted for mix of reasons including those traditionally associated with academic inquiry, as well as intentions to influence policy and practice. Differences in funding mechanisms, administrative and employment arrangements, and 'who' initiated the research, created differing incentives and perspectives for knowledge production. Factors associated with the characteristics and experience of the individuals involved also influenced goals, as did the type of research conducted. Policy agencies played a role in directing research to address policy needs. CONCLUSIONS: The findings of this study confirm that researchers are strongly influenced by their working environment. Funding schemes and other incentives to support policy relevant knowledge production are important. Contextual factors such as policy priorities, policy-driven research funding and the embedded nature or strong connections between some researchers and the policy agencies involved, are likely to have influenced the extent to which policy goals were reported in this study.


Assuntos
Política de Saúde , Obesidade Infantil , Pessoal Administrativo , Adulto , Austrália , Humanos , New South Wales , Obesidade Infantil/prevenção & controle
4.
BMC Pediatr ; 20(1): 373, 2020 08 08.
Artigo em Inglês | MEDLINE | ID: mdl-32770992

RESUMO

BACKGROUND: The greatest disease burden of sickle cell disease occurs early in life. Understanding factors that reduce disease related events in this period is therefore important. Hence, we assessed the impact of early care at a specialist center on the incidence of acute events during the first five years. METHODS: This was a retrospective cohort study among Jamaican children with sickle cell disease. Medical records of patients born January, 2004 to December, 2009, who were registered at the Sickle Cell Unit, a specialist care facility, were abstracted for dates of initiation to care, first occurrence and frequency of the outcomes of interest (vaso-occlusive crises, acute splenic sequestration, acute chest syndrome, and infection). Patients were classified according to whether initiation of care was before (early) or after 5 months of age (late). Using standardized t-tests, χ2 tests, and a multiple-failure survival analysis the rates of acute events between groups were compared. RESULTS: Of the total study group (n= 290), homozygous sickle cell disease accounted for 97% and 95% of the early (n=113) and late groups (n=177) respectively. The mean age of presentation in the early and late group was 0.2 and 2.3 years (p<0.01), with a mean length of follow-up of 5.2 and 3.2 years respectively (p<0.01). Vaso-occlusive crisis (n=880) and acute chest syndrome (n= 571) together accounted for 91.6% of the total number of events (n=1584). The risk of vaso-occlusive crisis and acute chest syndrome (among patients who presented with these acute events) was significantly higher in the "late" group, by 43% (Incidence rate ratio, (IRR) = 1.43, p<0.001); 95% CI (1.18-1.72) and 40% (IRR=1.40. p=0.002), 95% CI (1.12-1.75) respectively compared to "early" group. There was no difference in risk between groups for acute splenic sequestration and infection among persons presenting with these events. CONCLUSION: The risk of acute events in children with sickle cell disease exposed to early care at a specialist care is significantly less. Therefore, widespread screening with rapid referral to a specialist center stands to reduce substantial morbidity in Jamaica and other regions with high prevalence of sickle cell disease.


Assuntos
Síndrome Torácica Aguda , Anemia Falciforme , Síndrome Torácica Aguda/epidemiologia , Síndrome Torácica Aguda/etiologia , Anemia Falciforme/complicações , Anemia Falciforme/epidemiologia , Criança , Pré-Escolar , Homozigoto , Humanos , Lactente , Estudos Retrospectivos , Especialização
6.
Br J Haematol ; 181(2): 242-251, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29504121

RESUMO

This study investigated the association of nutritional and haematological variables with maximum time-averaged mean velocity (TAMV) measured by transcranial Doppler (TCD) velocity and the agreement of classification between two protocols. TCD categories included: normal (<170 cm/s), conditional (170-199 cm/s) and abnormal (≥200 cm/s) based on TAMV in distal internal carotid artery (dICA), middle cerebral artery (MCA), internal carotid bifurcation, anterior and posterior cerebral arteries. Of 358 children with sickle cell anaemia (SCA) examined, the mean age (±standard deviation) was 7·4 ± 2·7 years; 13·1% and 6·7% had conditional and abnormal velocities, respectively. Children with abnormal TCD velocities had higher prevalence of prior stroke (P = 0·006). Increased TAMV was associated with younger age (P = 0·001), lower weight (P = 0·001), height (P = 0·007) and oxygen saturation (P = 0·005). There was no association of TAMV with height-age or body mass index (BMI) z-scores. Adjusting for gender, BMI z-score, age, previous stroke and oxygen saturation, mean corpuscular volume (P = 0·005) and reticulocyte count (P = 0·013) were positively associated with TAMV, while haemoglobin concentration (P = 0·009) was negatively associated. There was good agreement [99%; weighted Kappa 0·98 (95% confidence interval 0·89-1), P = 0·0001] in TCD classification using data from five vessels versus two vessels (dICA and MCA). Haematological variables, rather than nutritional status, may be useful markers that identify high-risk children with SCA.


Assuntos
Anemia Falciforme , Artérias Cerebrais , Circulação Cerebrovascular , Hemoglobinas/metabolismo , Estado Nutricional , Ultrassonografia Doppler Transcraniana , Fatores Etários , Anemia Falciforme/sangue , Anemia Falciforme/diagnóstico por imagem , Anemia Falciforme/fisiopatologia , Biomarcadores/sangue , Velocidade do Fluxo Sanguíneo , Peso Corporal , Artérias Cerebrais/diagnóstico por imagem , Artérias Cerebrais/fisiopatologia , Criança , Pré-Escolar , Feminino , Humanos , Jamaica , Masculino , Fatores Sexuais
7.
Int J Behav Nutr Phys Act ; 15(1): 37, 2018 04 12.
Artigo em Inglês | MEDLINE | ID: mdl-29650023

RESUMO

BACKGROUND: Policies restricting children's exposure to unhealthy food marketing have been impeded by the lack of evidence showing a direct link between food advertising exposure and children's energy intake and body weight. Food advertising exposure increases children's immediate food consumption, but whether this increased intake is compensated for at later eating occasions is not known; consequently the sustained effect on diets remains unclear. METHODS: We conducted a within-subject, randomised, crossover, counterbalanced study across four, six-day holiday camps in New South Wales, Australia between April 2016 and January 2017. Children (7-12 years, n = 160) were recruited via local schools, email networks and social media. Two gender- and age-balanced groups were formed for each camp (n = 20), randomised to either a multiple- or single- media condition and exposed to food and non-food advertising in an online game and/or a television cartoon. Children's food consumption (kilojoules) was measured at a snack immediately after exposure and then at lunch later in the day. Linear mixed models were conducted to examine relationships between food advertising exposure and dietary intake, taking into account gender, age and weight status. RESULTS: All children in the multiple-media condition ate more at a snack after exposure to food advertising compared with non-food advertising; this was not compensated for at lunch, leading to additional daily food intake of 194 kJ (95% CI 80-308, p = 0.001, d = 0.2). Exposure to multiple-media food advertising compared with a single-media source increased the effect on snack intake by a difference of 182 kJ (95% CI 46-317, p = 0.009, d = 0.4). Food advertising had an increased effect among children with heavier weight status in both media groups. CONCLUSION: Online ('advergame') advertising combined with TV advertising exerted a stronger influence on children's food consumption than TV advertising alone. The lack of compensation at lunch for children's increased snack intake after food advertising exposure suggests that unhealthy food advertising exposure contributes to a positive energy-gap, which could cumulatively lead to the development of overweight. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry, number ACTRN12617001230347 (Retrospectively registered).


Assuntos
Publicidade , Dieta/psicologia , Ingestão de Energia , Internet , Televisão , Austrália , Criança , Comportamento Infantil , Estudos Cross-Over , Ingestão de Alimentos , Feminino , Humanos , Almoço , Masculino , Marketing , New South Wales , Sobrepeso , Estudos Retrospectivos , Lanches
8.
Appetite ; 125: 438-444, 2018 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-29496602

RESUMO

Exposure to unhealthy food marketing stimulates children's food consumption. A child's responsiveness is influenced by individual factors, resulting in an increased vulnerability to advertising effects among some children. Whether these differential responses may be altered by different parental feeding behaviours is unclear. The purpose of this study was to determine the relationship between parental feeding practices and children's food intake responses to food advertising exposure. A randomised, crossover, counterbalanced, within subject trial was conducted across four, six-day holiday camps in New South Wales, Australia between April 2016 and January 2017 with 160 children (7-12 years, n = 40/camp). Children were randomised to either a multiple media (TV and Internet) or single media (TV) condition and exposed to food (3 days) and non-food (3 days) advertising in an online game and/or a cartoon. Children's food consumption (kilojoules (kJ)) was measured at a snack immediately after advertising exposure and then at lunch later in the day. Parents completed the Child Feeding Questionnaire, and 'restriction' and 'pressure to eat' subscale scores were calculated. While food advertising affected all children in the multiple media condition, there was an increased effect on snack intake among children whose parents reported pressuring them to eat, with children consuming an additional 356 kJ after food advertising compared with non-food advertising. This was 209 kJ more than children whose parents did not pressure them to eat. In the single media condition, only children whose parents reported restrictive feeding practices ate more at lunch on food advertising days than non-food advertising days (240 kJ). These data highlight an increased susceptibility to food advertising among children whose parents report controlling feeding practices.


Assuntos
Comportamento Infantil , Ingestão de Energia , Comportamento Alimentar , Marketing/métodos , Relações Pais-Filho , Poder Familiar , Pais , Publicidade , Criança , Estudos Cross-Over , Ingestão de Alimentos , Feminino , Indústria Alimentícia , Humanos , Internet , Almoço , Masculino , New South Wales , Obesidade/etiologia , Autocontrole , Lanches , Inquéritos e Questionários , Televisão
9.
Health Res Policy Syst ; 16(1): 55, 2018 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-29950167

RESUMO

BACKGROUND: Citation of research in policy documents has been suggested as an indicator of the potential longer-term impacts of research. We investigated the use of research citations in childhood obesity prevention policy documents from New South Wales (NSW), Australia, considering the feasibility and value of using research citation as a proxy measure of research impact. METHODS: We examined childhood obesity policy documents produced between 2000 and 2015, extracting childhood obesity-related references and coding these according to reference type, geographical origin and type of research. A content analysis of the policy documents examined where and how research was cited in the documents and the context of citation for individual research publications. RESULTS: Over a quarter (28%) of the policy documents (n = 86) were not publicly available, almost two-thirds (63%) contained references, half (47%) cited obesity-related research and over a third (41%) of those containing references used unorthodox referencing styles, making reference extraction laborious. No patterns, in terms of the types of documents more likely to cite research, were observed and the number of obesity research publications cited per document was highly variable. In total, 263 peer-reviewed and 94 non-peer-reviewed obesity research publications were cited. Research was most commonly cited to support a policy argument or choice of solution. However, it was not always possible to determine how or why individual publications were cited or whether the cited research itself had influenced the policy process. Content analysis identified circumstances where research was mentioned or considered, but not directly cited. CONCLUSIONS: Citation of research in policy documents in this case did not always provide evidence that the cited research had influenced the policy process, only that it was accessible and relevant to the content of the policy document. Research citation across these public health policy documents varied greatly and is unlikely to be an accurate reflection of actual research use by the policy agencies involved. The links between citation and impact may be more easily drawn in specific policy areas or types of documents (e.g. clinical guidelines), where research appraisal feeds directly into policy recommendations.


Assuntos
Bibliometria , Pesquisa Biomédica , Política de Saúde , Obesidade Infantil/prevenção & controle , Publicações , Editoração , Humanos , New South Wales
10.
Health Res Policy Syst ; 16(1): 54, 2018 Jun 25.
Artigo em Inglês | MEDLINE | ID: mdl-29940961

RESUMO

BACKGROUND: Measuring the policy and practice impacts of research is becoming increasingly important. Policy impacts can be measured from two directions - tracing forward from research and tracing backwards from a policy outcome. In this review, we compare these approaches and document the characteristics of studies assessing research impacts on policy and the policy utilisation of research. METHODS: Keyword searches of electronic databases were conducted in December 2016. Included studies were published between 1995 and 2016 in English and reported methods and findings of studies measuring policy impacts of specified health research, or research use in relation to a specified health policy outcome, and reviews reporting methods of research impact assessment. Using an iterative data extraction process, we developed a framework to define the key elements of empirical studies (assessment reason, assessment direction, assessment starting point, unit of analysis, assessment methods, assessment endpoint and outcomes assessed) and then documented the characteristics of included empirical studies according to this framework. RESULTS: We identified 144 empirical studies and 19 literature reviews. Empirical studies were derived from two parallel streams of research of equal size, which we termed 'research impact assessments' and 'research use assessments'. Both streams provided insights about the influence of research on policy and utilised similar assessment methods, but approached measurement from opposite directions. Research impact assessments predominantly utilised forward tracing approaches while the converse was true for research use assessments. Within each stream, assessments focussed on narrow or broader research/policy units of analysis as the starting point for assessment, each with associated strengths and limitations. The two streams differed in terms of their relative focus on the contributions made by specific research (research impact assessments) versus research more generally (research use assessments) and the emphasis placed on research and the activities of researchers in comparison to other factors and actors as influencers of change. CONCLUSIONS: The Framework presented in this paper provides a mechanism for comparing studies within this broad field of research enquiry. Forward and backward tracing approaches, and their different ways of 'looking', tell a different story of research-based policy change. Combining approaches may provide the best way forward in terms of linking outcomes to specific research, as well as providing a realistic picture of research influence.


Assuntos
Pesquisa Biomédica , Atenção à Saúde , Medicina Baseada em Evidências , Política de Saúde , Humanos
11.
Vet Radiol Ultrasound ; 58(4): 381-388, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28335088

RESUMO

Idiopathic pulmonary fibrosis is an interstitial lung disease of unknown etiology resulting in progressive interstitial fibrosis, with a known predilection in West Highland white terriers. In humans, computed tomography (CT) is a standard method for providing diagnostic and prognostic information, and plays a major role in the idiopathic pulmonary fibrosis staging process. Objectives of this retrospective, analytical, cross-sectional study were to establish descriptive criteria for reporting CT findings and test correlations among CT, clinical findings and survival time in West Highland white terriers with idiopathic pulmonary fibrosis. Inclusion criteria for affected West Highland white terriers were a diagnosis of idiopathic pulmonary fibrosis and available CT, bronchoscopy, bronchoalveolar lavage, echocardiography, and routine blood analysis findings. Clinically normal West Highland white terriers were recruited for the control group. Survival times were recorded for affected dogs. The main CT lung pattern and clinical data were blindly and separately graded as mild, moderate, or severe. Twenty-one West Highland white terriers with idiopathic pulmonary fibrosis and 11 control West Highland white terriers were included. The severity of pulmonary CT findings was positively correlated with severity of clinical signs (ρ = 0.48, P = 0.029) and negatively associated with survival time after diagnosis (ρ = -0.56, P = 0.025). Affected dogs had higher lung attenuation (median: -563 Hounsfield Units (HU)) than control dogs (median: -761 HU), (P < 0.001). The most common CT characteristics were ground-glass pattern (16/21) considered as a mild degree of severity, and focal reticular and mosaic ground-glass patterns (10/21) considered as a moderate degree of severity. Findings supported the use of thoracic CT as a method for characterizing idiopathic pulmonary fibrosis in West Highland white terriers and providing prognostic information for owners.


Assuntos
Doenças do Cão/diagnóstico por imagem , Fibrose Pulmonar Idiopática/veterinária , Animais , Estudos Transversais , Doenças do Cão/diagnóstico , Cães , Feminino , Fibrose Pulmonar Idiopática/diagnóstico , Fibrose Pulmonar Idiopática/diagnóstico por imagem , Masculino , Prognóstico , Valores de Referência , Estudos Retrospectivos , Tomografia Computadorizada por Raios X/veterinária
12.
Public Health Nutr ; 19(16): 2940-2948, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27293177

RESUMO

OBJECTIVE: The formation of food brand associations and attachment is fundamental to brand preferences, which influence purchases and consumption. Food promotions operate through a cascade of links, from brand recognition, to affect, and on to consumption. Frequent exposures to product promotions may establish social norms for products, reinforcing brand affect. These pathways signify potential mechanisms for how children's exposure to unhealthy food promotions can contribute to poor diets. The present study explored children's brand associations and attachments for major food brands. DESIGN: A cross-sectional online survey was conducted. Fourteen study brands were used, with each child viewing a set of seven logos. The questionnaire assessed perceptions of food brands and perceptions of users of brands, using semantic differential scales, and perceived brand 'personalities', using Likert scales. SETTING: New South Wales, Australia, October-November 2014. SUBJECTS: Children aged 10-16 years (n 417). RESULTS: Children demonstrated strong positive affect to certain brands, perceiving some unhealthy food brands to have positive attributes, desirable user traits and alignment to their own personality. Brand personality traits of 'smart' and 'sporty' were viewed as indicators of healthiness. Brands with these traits were ranked lower for popularity. CONCLUSIONS: Children's brand associations and attachments indicate the potential normative social influences of promotions. While children are aware of brand healthiness as an attribute, this competes with other brand associations, highlighting the challenge of health/nutrition messaging to counter unhealthy food marketing. Restricting children's exposure to unhealthy food marketing and the persuasive nature of marketing is an important part of efforts to improve children's diet-related health.


Assuntos
Publicidade , Indústria Alimentícia , Preferências Alimentares , Marketing , Adolescente , Criança , Estudos Transversais , Feminino , Humanos , Masculino , New South Wales
13.
Health Promot Int ; 31(1): 144-52, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24997194

RESUMO

There is an established link between food promotions and children's food purchase and consumption. Children in developing countries may be more vulnerable to food promotions given the relative novelty of advertising in these markets. This study aimed to determine the scope of television food advertising to children across the Asia-Pacific to inform policies to restrict this marketing. Six sites were sampled, including from China, Indonesia, Malaysia and South Korea. At each site, 192 h of television were recorded (4 days, 16 h/day, three channels) from May to October 2012. Advertised foods were categorized as core/healthy, non-core/unhealthy or miscellaneous, and by product type. Twenty-seven percent of advertisements were for food/beverages, and the most frequently advertised product was sugar-sweetened drinks. Rates of non-core food advertising were highest during viewing times most popular with children, when between 3 (South Korea) and 15 (Indonesia) non-core food advertisements were broadcast each hour. Children in the Asia-Pacific are exposed to high volumes of unhealthy food/beverage television advertising. Different policy arrangements for food advertising are likely to contribute to regional variations in advertising patterns. Cities with the lowest advertising rates can be identified as exemplars of good policy practice.


Assuntos
Publicidade/estatística & dados numéricos , Alimentos , Televisão , Sudeste Asiático , Bebidas , Criança , Pré-Escolar , Países em Desenvolvimento , Humanos
14.
J Pediatr ; 167(3): 702-5.e1, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26163082

RESUMO

OBJECTIVE: To compare mortality in children <5 years of age with sickle cell disease (SCD) in Jamaica, a resource-limited country, diagnosed by newborn screening and managed in a comprehensive care facility, to that of the general population. STUDY DESIGN: The study was carried out at the Sickle Cell Unit in Kingston, Jamaica. We determined the status (dead/alive) at age 5 years in a cohort of 548 children with SCD diagnosed by newborn screening and managed at the Sickle Cell Unit during the period November 1995 to December 2009. The standardized mortality ratio was calculated using World Health Organization life tables for reference mortality. RESULTS: Eight deaths (1.5%) occurred in children <5 years of age during the study period. The mean age at death was 2.0 ± 1.5 years. The overall mortality incidence in children <5 years of age was 3.1 (95% CI 1.6, 6.2) per 1000 person-years with a standardized mortality ratio of 0.52 (95% CI 0.3, 1.0). CONCLUSIONS: Mortality in children <5 years of age with SCD diagnosed at birth and managed at a comprehensive care clinic in Jamaica is equivalent to that of the general population. Children with SCD, a highly vulnerable population, can be effectively managed, even in resource-limited environments.


Assuntos
Instituições de Assistência Ambulatorial , Anemia Falciforme/mortalidade , Anemia Falciforme/diagnóstico , Pré-Escolar , Estudos de Coortes , Países em Desenvolvimento , Feminino , Seguimentos , Humanos , Incidência , Lactente , Recém-Nascido , Jamaica/epidemiologia , Masculino , Triagem Neonatal , Estudos Retrospectivos , Talassemia beta/diagnóstico , Talassemia beta/mortalidade
15.
Pediatr Blood Cancer ; 62(10): 1862-4, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25929458

RESUMO

We undertook a cost effectiveness analysis (CEA) of hydroxyurea (HU) in preventing stroke recurrence and/or death. We followed 43 children with sickle cell disease from 2000 to 2009 after having a first clinical stroke, of whom 10 opted for HU therapy. HU use led to decreased stroke recurrence and death without significantly increasing the annual cost of care per patient (J$83,250 vs. J$76,901, P = 0.491). The incremental cost effectiveness ratio (ICER) for prevention of stroke recurrence amounted to J$169,238 (US$1,900), while that for death prevention equalled J$635,843 (US$7,140). HU may be recommended when safe and affordable transfusion therapy is not feasible.


Assuntos
Anemia Falciforme/complicações , Antidrepanocíticos/uso terapêutico , Análise Custo-Benefício , Hidroxiureia/uso terapêutico , Acidente Vascular Cerebral/prevenção & controle , Anemia Falciforme/tratamento farmacológico , Anemia Falciforme/economia , Antidrepanocíticos/economia , Criança , Países em Desenvolvimento , Feminino , Humanos , Hidroxiureia/economia , Jamaica , Masculino , Recidiva , Acidente Vascular Cerebral/etiologia
16.
Med J Aust ; 203(4): 184e.1-4, 2015 Aug 17.
Artigo em Inglês | MEDLINE | ID: mdl-26268288

RESUMO

OBJECTIVE: To describe the research publication outputs from intervention research funded by Australia's National Health and Medical Research Council (NHMRC). DESIGN AND SETTING: Analysis of descriptive data and data on publication outputs collected between 23 July 2012 and 10 December 2013 relating to health intervention research project grants funded between 1 January 2003 and 31 December 2007. MAIN OUTCOME MEASURES: Stages of development of intervention studies (efficacy, effectiveness, replication, adaptation or dissemination of intervention); types of interventions studied; publication output per NHMRC grant; and whether interventions produced statistically significant changes in primary outcome variables. RESULTS: Most of the identified studies tested intervention efficacy or effectiveness in clinical or community settings, with few testing the later stages of intervention development, such as replication, adaptation or dissemination. Studies focused largely on chronic disease treatment and management, and encompassed various medical and allied health disciplines. Equal numbers of studies had interventions that produced statistically significant results on primary outcomes, (27) and those that did not (27). The mean number of total published articles per grant was 3.3, with 2.0 articles per grant focusing on results, and the remainder covering descriptive, exploratory or methodological aspects of intervention research. CONCLUSIONS: Our study provides a benchmark for the publication outputs of NHMRC-funded health intervention research in Australia. Research productivity is particularly important for intervention research, where findings are likely to have more immediate and direct applicability to health policy and practice. Tracking research outputs in this way provides information on whether current research investment patterns match the need for evidence about health care interventions.


Assuntos
Pesquisa Biomédica/estatística & dados numéricos , Publicações/estatística & dados numéricos , Austrália , Humanos , Publicações Periódicas como Assunto/estatística & dados numéricos , Apoio à Pesquisa como Assunto/estatística & dados numéricos
17.
Health Res Policy Syst ; 13: 3, 2015 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-25552272

RESUMO

BACKGROUND: There is a growing emphasis on the importance of research having demonstrable public benefit. Measurements of the impacts of research are therefore needed. We applied a modified impact assessment process that builds on best practice to 5 years (2003-2007) of intervention research funded by Australia's National Health and Medical Research Council to determine if these studies had post-research real-world policy and practice impacts. METHODS: We used a mixed method sequential methodology whereby chief investigators of eligible intervention studies who completed two surveys and an interview were included in our final sample (n = 50), on which we conducted post-research impact assessments. Data from the surveys and interviews were triangulated with additional information obtained from documentary analysis to develop comprehensive case studies. These case studies were then summarized and the reported impacts were scored by an expert panel using criteria for four impact dimensions: corroboration; attribution, reach, and importance. RESULTS: Nineteen (38%) of the cases in our final sample were found to have had policy and practice impacts, with an even distribution of high, medium, and low impact scores. While the tool facilitated a rigorous and explicit criterion-based assessment of post-research impacts, it was not always possible to obtain evidence using documentary analysis to corroborate the impacts reported in chief investigator interviews. CONCLUSIONS: While policy and practice is ideally informed by reviews of evidence, some intervention research can and does have real world impacts that can be attributed to single studies. We recommend impact assessments apply explicit criteria to consider the corroboration, attribution, reach, and importance of reported impacts on policy and practice. Impact assessments should also allow sufficient time between impact data collection and completion of the original research and include mechanisms to obtain end-user input to corroborate claims and reduce biases that result from seeking information from researchers only.


Assuntos
Pesquisa sobre Serviços de Saúde/estatística & dados numéricos , Avaliação de Programas e Projetos de Saúde/métodos , Pesquisa Translacional Biomédica , Prática Clínica Baseada em Evidências , Política de Saúde , Humanos
18.
Health Promot J Austr ; 26(1): 52-56, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26149255

RESUMO

ISSUE ADDRESSED: Marketing of products harmful to the health of children has been found to be prolific, and occurs across multiple media platforms and in several settings, including organised sport, thus potentially undermining the health benefits inherent in sports participation. Through website audits, this study investigated the nature and extent of unhealthy food, beverage, alcohol and gambling sponsorship across peak Australian sporting organisations. METHODS: A structured survey tool identified and assessed sponsoring companies and products displayed on the websites of the 53 national and state/territory sport governing bodies in Australia receiving government funding. Identified products were categorised as healthy or unhealthy, based on criteria developed by health experts. RESULTS: There was a total of 413 websites operated by the 53 sports, with 1975 company or product sponsors identified. Overall, 39 sports had at least one unhealthy sponsor, and 10% of all sponsors were rated as unhealthy. Cricket had the highest percent of unhealthy sponsors (27%) and the highest number of unhealthy food and beverage sponsors (n=19). Rugby Union (n=16) and Australian Football (n=4) had the highest numbers of alcohol and gambling sponsors respectively. CONCLUSIONS: Sponsorship of Australian sport governing bodies by companies promoting unhealthy food and beverage, alcohol and gambling products is prevalent at the state/territory and national level. SO WHAT?: Regulatory guidelines should be established to limit such sponsorship and ensure that it is not translated into promotions that may reach and influence children.


Assuntos
Consumo de Bebidas Alcoólicas , Bebidas , Alimentos , Jogo de Azar , Marketing Social , Esportes/economia , Austrália , Criança , Financiamento Governamental , Humanos , Internet , Valores Sociais
19.
Am J Public Health ; 104(12): e56-64, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25322294

RESUMO

OBJECTIVES: We assessed the amount, reach, and nature of energy-dense, nutrient-poor (EDNP) food and beverage marketing on Facebook. METHODS: We conducted a content analysis of the marketing techniques used by the 27 most popular food and beverage brand Facebook pages in Australia. We coded content across 19 marketing categories; data were collected from the day each page launched (mean = 3.65 years of activity per page). RESULTS: We analyzed 13 international pages and 14 Australian-based brand pages; 4 brands (Subway, Coca-Cola, Slurpee, Maltesers) had both national and international pages. Pages widely used marketing features unique to social media that increase consumer interaction and engagement. Common techniques were competitions based on user-generated content, interactive games, and apps. Four pages included apps that allowed followers to place an order directly through Facebook. Adolescent and young adult Facebook users appeared most receptive to engaging with this content. CONCLUSIONS: By using the interactive and social aspects of Facebook to market products, EDNP food brands capitalize on users' social networks and magnify the reach and personal relevance of their marketing messages.


Assuntos
Bebidas , Alimentos , Marketing/métodos , Mídias Sociais/estatística & dados numéricos , Austrália , Humanos
20.
Public Health Nutr ; 17(5): 979-86, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-23182377

RESUMO

OBJECTIVE: The present study investigated parents' understanding and approaches to providing energy-dense and nutrient-poor 'extra foods' to pre-school children and explored variation between parents of low and high socio-economic status in relation to these issues. DESIGN: We conducted thirteen focus groups. Data were subject to framework analysis. SETTING: Child-care centres in distinctly socially disadvantaged and socially advantaged areas. SUBJECTS: Eighty-eight parents of children aged 3-5 years. RESULTS: The three most common terms parents identified to describe foods that are not 'everyday foods' were 'treats', 'sometimes foods' and 'junk'. Parents' perceptions regarding what influences them in providing food to their children included seven sub-themes: (i) the influence of the child; (ii) food-related parenting practices; (iii) health considerations; (iv) food costs and convenience; (v) external factors perceived as influencing their child; (vi) factors related to child care; and (vii) social influences and occasions. Parents' decision-making processes regarding provision of 'extra foods' related to moderation and balance. Parents generally expressed the position that as long as a child is eating healthy foods, then treats are appropriate; and for many parents, this might apply frequently. All groups described the health of their child as an influence, but parents in low socio-economic groups were more likely to describe immediate concerns (dental health, behaviour) in relation to avoiding sugar-dense food or drink. CONCLUSIONS: The belief that provision of 'extra foods' can be frequent as long as children are eating a healthy balance of foods is factored into parents' decision making. Challenging this belief may be important for reducing the consumption of 'extra foods' by young children.


Assuntos
Dieta , Ingestão de Energia , Comportamento Alimentar , Conhecimentos, Atitudes e Prática em Saúde , Poder Familiar , Pais , Adulto , Pré-Escolar , Tomada de Decisões , Feminino , Grupos Focais , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/etiologia , Pesquisa Qualitativa , Classe Social
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