Detalhe da pesquisa
1.
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.
Mol Cell
; 83(14): 2417-2433.e7, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37348497
2.
Interactions between lineage-associated transcription factors govern haematopoietic progenitor states.
EMBO J
; 39(24): e104983, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33103827
3.
Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation.
EMBO J
; 39(8): e104270, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32149421
4.
STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.
Blood
; 140(14): 1592-1606, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35767701
5.
Reconstructing blood stem cell regulatory network models from single-cell molecular profiles.
Proc Natl Acad Sci U S A
; 114(23): 5822-5829, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584094
6.
ConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sites.
Nucleic Acids Res
; 44(8): e72, 2016 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721389
7.
Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells.
Nucleic Acids Res
; 42(22): 13513-24, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25428352
8.
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.
Blood
; 122(14): e12-22, 2013 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23974199
9.
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.
Blood
; 122(15): 2694-703, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23974202
10.
A time- and single-cell-resolved model of murine bone marrow hematopoiesis.
Cell Stem Cell
; 31(2): 244-259.e10, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38183977
11.
ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.
Blood
; 117(26): 7079-89, 2011 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536859
12.
Yolk sac cell atlas reveals multiorgan functions during human early development.
Science
; 381(6659): eadd7564, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37590359
13.
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice.
Mol Metab
; 66: 101604, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36184065
14.
Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML.
Nat Commun
; 11(1): 1407, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32179751
15.
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.
Cancer Discov
; 9(12): 1736-1753, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31662298
16.
An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability.
Elife
; 5: e11469, 2016 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26901438
17.
Mapping and functional characterisation of a CTCF-dependent insulator element at the 3' border of the murine Scl transcriptional domain.
PLoS One
; 7(3): e31484, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396734
18.
Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.
Mol Cell Biol
; 30(15): 3853-63, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20516218