Detalhe da pesquisa
1.
Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling.
J Biol Chem
; 292(23): 9711-9720, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28424266
2.
Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1).
J Biol Chem
; 291(7): 3385-94, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26710850
3.
Versatile Signaling Activity of Adhesion GPCRs.
Handb Exp Pharmacol
; 234: 127-146, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27832487
4.
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance.
Nat Cancer
; 4(6): 812-828, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277530
5.
Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma.
Clin Cancer Res
; 27(11): 3190-3200, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568347
6.
A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK.
Cancer Cell
; 35(3): 457-472.e5, 2019 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773340
7.
Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma.
Clin Cancer Res
; 27(16): 4664, 2021 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34389658