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1.
Anticancer Res ; 22(4): 2373-6, 2002.
Artigo em Inglês | MEDLINE | ID: mdl-12174929

RESUMO

This paper introduces an innovative technique of highly conservative limb-saving surgery for juxta-articular osteosarcoma. This technique consists of marginal tumour excision, joint preservation and reconstruction by distraction osteogenesis. Ten patients, with a mean age of 19.5 years and high-grade osteosarcoma, underwent this procedure. The distal femur and proximal tibia were affected in five patients each. After effective pre-operative chemotherapy, the tumour was excised with preservation of the epiphysis, the articular surface and the maximun amount of healthy soft tissue. This was followed by application of an external fixator. Bone transport was performed for seven patients and shortening-distraction for three. The limb function was rated excellent in seven patients, good in one and fair in two. At the final follow-up, three patients were dead after a mean of 25.3 months while seven patients remained free of disease with a mean follow-up of 55.4 months. Joint preservation and biological reconstruction through distraction osteogenesis can produce excellent and long-lasting functional results.


Assuntos
Neoplasias Ósseas/cirurgia , Articulações/cirurgia , Osteogênese por Distração/métodos , Osteossarcoma/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Neoplasias Ósseas/diagnóstico , Neoplasias Ósseas/patologia , Neoplasias Femorais/diagnóstico , Neoplasias Femorais/patologia , Neoplasias Femorais/cirurgia , Humanos , Osteossarcoma/diagnóstico , Osteossarcoma/patologia , Tíbia/cirurgia , Resultado do Tratamento
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