Detalhe da pesquisa
1.
Lipidomic-Based Approach to 10 s Classification of Major Pediatric Brain Cancer Types with Picosecond Infrared Laser Mass Spectrometry.
Anal Chem
; 96(3): 1019-1028, 2024 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38190738
2.
A Workflow for Meaningful Interpretation of Classification Results from Handheld Ambient Mass Spectrometry Analysis Probes.
Int J Mol Sci
; 25(6)2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542461
3.
Metabolic Lipids in Melanoma Enable Rapid Determination of Actionable BRAF-V600E Mutation with Picosecond Infrared Laser Mass Spectrometry in 10 s.
Anal Chem
; 95(38): 14430-14439, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695851
4.
Picosecond Infrared Laser Mass Spectrometry Identifies a Metabolite Array for 10 s Diagnosis of Select Skin Cancer Types: A Proof-of-Concept Feasibility Study.
Anal Chem
; 94(48): 16821-16830, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395434
5.
Mass Spectrometry Imaging Reveals a Gradient of Cancer-like Metabolic States in the Vicinity of Cancer Not Seen in Morphometric Margins from Microscopy.
Anal Chem
; 93(10): 4408-4416, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33651938
6.
Nanoparticle Formulation Derived from Carboxymethyl Cellulose, Polyethylene Glycol, and Cabazitaxel for Chemotherapy Delivery to the Brain.
Bioconjug Chem
; 29(6): 2009-2020, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29734804
7.
Discovery of Conformationally Constrained ALK2 Inhibitors.
J Med Chem
; 67(6): 4707-4725, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498998
8.
Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.
ACS Med Chem Lett
; 14(2): 199-210, 2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793435
9.
Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity.
Cell Chem Biol
; 30(7): 795-810.e8, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37369212
10.
Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of 11C-Labeled ALK2 Inhibitors.
ACS Med Chem Lett
; 12(5): 846-850, 2021 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34055235
11.
Structure-Activity Relationship of USP5 Inhibitors.
J Med Chem
; 64(20): 15017-15036, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34648286
12.
A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity.
JCI Insight
; 6(5)2021 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33476303
13.
Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma.
J Med Chem
; 64(15): 11129-11147, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34291633
14.
Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
J Mol Biol
; 433(23): 167294, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662547
15.
Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.
J Med Chem
; 63(9): 4978-4996, 2020 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32369358
16.
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma.
J Med Chem
; 63(17): 10061-10085, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787083
17.
Automated molecular formula determination by tandem mass spectrometry (MS/MS).
Analyst
; 134(4): 690-700, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19305917
18.
Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales.
Cancer Res
; 79(9): 2426-2434, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890619
19.
One-step purification of palmatine and its derivative dl-tetrahydropalmatine from Enantia chlorantha using high-performance displacement chromatography.
J Chromatogr A
; 1208(1-2): 47-53, 2008 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18804774
20.
Cabazitaxel-conjugated nanoparticles for docetaxel-resistant and bone metastatic prostate cancer.
Cancer Lett
; 410: 169-179, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28965854