Detalhe da pesquisa
1.
Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Blood
; 142(1): 44-61, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37023372
2.
CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.
Blood
; 141(20): 2508-2519, 2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800567
3.
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Prostate
; 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38619005
4.
A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML.
Blood
; 137(24): 3403-3415, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33690798
5.
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Nature
; 481(7380): 157-63, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22237106
6.
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.
Blood
; 126(22): 2479-83, 2015 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26443624
7.
Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis.
Blood
; 124(14): 2280-4, 2014 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25115888
8.
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms.
Blood
; 123(13): 2075-83, 2014 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24470592
9.
Mathematical modeling reveals alternative JAK inhibitor treatment in myeloproliferative neoplasms.
Haematologica
; 105(3): e91-e94, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413098
10.
Mutation of the receptor tyrosine phosphatase PTPRC (CD45) in T-cell acute lymphoblastic leukemia.
Blood
; 119(19): 4476-9, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22438252
11.
New pieces of a puzzle: the current biological picture of MPN.
Biochim Biophys Acta
; 1826(2): 415-22, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22824378
12.
PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.
Blood
; 117(26): 7090-8, 2011 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21551237
13.
Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms.
Haematologica
; 103(1): e5-e9, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29051283
14.
MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context.
Haematologica
; 96(5): 779-83, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21193420
15.
Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin's lymphoma and T-cell non-Hodgkin's lymphoma.
Haematologica
; 96(11): 1723-7, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21791476
16.
Evaluating Clonal Hematopoiesis in Tumor-Infiltrating Leukocytes in Breast Cancer and Secondary Hematologic Malignancies.
J Natl Cancer Inst
; 112(1): 107-110, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504684
17.
Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.
J Clin Invest
; 129(4): 1596-1611, 2019 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30730307
18.
Underlying Causes and Therapeutic Targeting of the Inflammatory Tumor Microenvironment.
Front Cell Dev Biol
; 6: 56, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29946544
19.
LSD1 Inhibition Prolongs Survival in Mouse Models of MPN by Selectively Targeting the Disease Clone.
Hemasphere
; 2(3): e54, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723778
20.
TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.
Cell Rep
; 22(5): 1250-1262, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29386112