Detalhe da pesquisa
1.
ß-Alanine and N-terminal cationic substituents affect polyamide-DNA binding.
Org Biomol Chem
; 15(46): 9880-9888, 2017 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29143012
2.
Modulation of DNA-polyamide interaction by ß-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.
Org Biomol Chem
; 12(38): 7523-36, 2014 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25141096
3.
Fluorescence assay of polyamide-DNA interactions.
Anal Biochem
; 423(1): 178-83, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342620
4.
Interactions of two large antiviral polyamides with the long control region of HPV16.
Biochimie
; 127: 103-14, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27155361
5.
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1).
J Med Chem
; 48(18): 5837-52, 2005 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16134950
6.
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2).
J Med Chem
; 48(18): 5853-68, 2005 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16134951
7.
Binding studies of a large antiviral polyamide to a natural HPV sequence.
Biochimie
; 102: 83-91, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24582833
8.
DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral Agents.
Med Chem (Los Angeles)
; 4: 338-344, 2014 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24839583
9.
Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with ß-alanine.
Biochimie
; 95(2): 271-9, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23023196
10.
HPV episome levels are potently decreased by pyrrole-imidazole polyamides.
Antiviral Res
; 91(2): 177-86, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21669229