[Body weight increase and quality of semen: a controversial association]. / Aumento del peso corporal y calidad seminal: una asociación controvertida.

BACKGROUND: Infertility is a public health disorder affecting 10% of the population worldwide. Research on the impact of body mass index (BMI) on male fertility is very limited as compared to the multiple studies evaluating the impact of overweight in women's fertility. Although 25%-30% of the cases of couples consulting for infertility are attributable to male factors, studies evaluating the association between semen parameters and BMI are controversial. OBJECTIVE: To assess the impact of BMI on semen parameters in a selected group of men with unexplained infertility. METHOD: A retrospective analysis of 168 patients during the 2008-2010 period. They all had at least one semen analysis and related studies to rule out known causes of infertility. Median age of patients was 35 years (22-55), and they were divided into three groups: normal weight (BMI: 20-24.9kg/m(2)), overweight (BMI 25-29.9kg/m(2)), and obese (BMI ≥30kg/m(2)). RESULTS: There were no significant differences in semen parameters evaluated between the three groups, and no significant correlation was found between the same parameters and BMI. CONCLUSIONS: There was no significant association between BMI and conventional semen parameters, but we cannot exclude an impairment in other semen parameters that are not routinely assessed, which could result in a lower potential fertility in these individuals.

Reference values of parathyroid hormone and vitamin D Hormone by chemiluminescent automated assay / Valores de referencia de hormona paratiroidea y vitamina D por método quimioluminiscente automatizado en perros

Objective. Provide reference data for parathyroid hormone 1-84 (PTH 1-84) and 25OH Vitamin D (25OH D) using a new technique. Materials and methods. The hormones were evaluated, in serum, using a third generation automated chemiluminescent method for PTH in a group of 60 adult dogs, clinically healthy, grouped according to age in years in GA: 1 to 5, GB: 6 to 10 and GC:>10. Results. Data expressed as average ± DS were for PTH (pg/ml): 9.3±2.3; 12±6.3; 12.2±3.7; and for 25OH D (ng/ml): 84.2±27.8; 68.2±16.0; 63.6±23.1, respectively. The PTH value was significantly greater (p<0.05) in groups B and C in comparison with A, but no significant differences were observed between GB and GC. The 25OH D concentration was significantly less in GB (p<0.05) and in GC (p<0.01) in comparison with GA, showing no differences between GB and GC. A negative correlation between 25OH D and PTH was found (r= -0.28; p=0.015). Conclusions. Data contributed by this study provide reference values for PTH 1-84 and 25OH D, evaluated using a third generation automated chemiluminescent method for PTH in local dogs. The results will facilitate monitoring diseases that alter the metabolism of calcium and phosphorus in dogs.

Objetivo. Aportar datos de referencia, para hormona paratiroidea 1-84 (PTH 1-84) y 25OH Vitamina D (25OH D) con una nueva técnica. Materiales y métodos. Las hormonas fueron valoradas, en suero, por un método quimioluminiscente automatizado, y de tercera generación para la PTH, en una población de 60 perros adultos clínicamente sanos, agrupados según edad en años en GA: 1 a 5, GB: 6 a 10 y GC:>10. Resultados. Los datos expresados como media ± DS fueron para la PTH (pg/ml): 9.3±2.3; 12±6.3; 12.2±3.7; y para la 25OH D (ng/ml): 84.2±27.8; 68.2±16.0; 63.6±23.1, respectivamente. El valor de PTH fue significativamente mayor (p<0.05) en los grupos B y C con respecto al A, pero no se observó diferencia significativa entre GB y GC. La concentración de 25OH D fue significativamente menor en el GB (p<0.05) y en el GC (p<0.01) con respecto al GA, sin haber diferencias entre los GB y GC. Se encontró una correlación negativa entre 25OH D y PTH (r= -0.28; p=0.015). Conclusiones. Los datos aportados en este trabajo permiten disponer de valores de referencia de PTH 1-84 y de 25OH D, valorados por un método quimioluminiscente automatizado y de tercera generación para la PTH, en una población local de perros. Los resultados facilitarán el seguimiento de enfermedades que alteran el metabolismo del calcio y fósforo en perros.

Aumento del peso corporal y calidad seminal: una asociación controvertida / Body weight increase and quality of semen: a controversial association

Antecedentes La infertilidad es un problema de salud que afecta aproximadamente al 10% de la población mundial. La investigación del impacto del índice de masa corporal (IMC) sobre la fertilidad masculina es limitada comparada con los estudios realizados en mujeres. A pesar de que en el 25-30% de los casos de infertilidad de pareja el factor es exclusivamente masculino, los estudios sobre parámetros seminales e IMC son controvertidos. Objetivo Evaluar el impacto del IMC sobre los parámetros seminales en una población seleccionada de hombres que consultaron por infertilidad sin causa aparente. Método Análisis retrospectivo sobre 168 pacientes durante el período 2008-2010. Todos contaban al menos con un espermiograma y estudios correspondientes para descartar causas conocidas de infertilidad. La mediana de edad de los pacientes fue de 35 años (22–55). Fueron divididos en 3 grupos: normopeso (IMC: 20-24.9 kg/m2) sobrepeso (IMC 25-29.9 kg/m2) y obesos (IMC ≥ 30 kg/m2).Resultados No se encontraron diferencias significativas de los diversos parámetros evaluados entre los distintos grupos de IMC. Tampoco se halló correlación significativa entre esos mismos parámetros y el IMC. Conclusiones No existió una asociación entre el IMC y los parámetros convencionales del semen, pero no podemos descartar que exista una afectación de otros parámetros seminales, no evaluados rutinariamente, que podrían provocar menor potencial de fertilidad en estos individuos (AU)

Background Infertility is a public health disorder affecting 10% of the population worldwide. Research on the impact of body mass index (BMI) on male fertility is very limited as compared to the multiple studies evaluating the impact of overweight in women's fertility. Although 25%-30% of the cases of couples consulting for infertility are attributable to male factors, studies evaluating the association between semen parameters and BMI are controversial. Objective To assess the impact of BMI on semen parameters in a selected group of men with unexplained infertility. Method A retrospective analysis of 168 patients during the 2008-2010 period. They all had at least one semen analysis and related studies to rule out known causes of infertility. Median age of patients was 35 years (22-55), and they were divided into three groups: normal weight (BMI: 20-24.9 kg/m2), overweight (BMI 25-29.9 kg/m2), and obese (BMI ≥ 30 kg/m2).Results There were no significant differences in semen parameters evaluated between the three groups, and no significant correlation was found between the same parameters and BMI. Conclusions There was no significant association between BMI and conventional semen parameters, but we cannot exclude an impairment in other semen parameters that are not routinely assessed, which could result in a lower potential fertility in these individuals (AU)