Detalhe da pesquisa
1.
Inactivation of VRK1 sensitizes ovarian cancer to PARP inhibition through regulating DNA-PK stability.
Exp Cell Res
; 438(1): 114036, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38614421
2.
Degradation of AZGP1 suppresses apoptosis and facilitates cholangiocarcinoma tumorigenesis via TRIM25.
J Cell Mol Med
; 28(3): e18104, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38183356
3.
DGG-300273, a novel WNT/ß-catenin inhibitor, induces apoptotic cell death by activating ROS-BIM signaling in a Wnt-dependent manner in colon cancer cells.
Invest New Drugs
; 41(1): 105-114, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36538258
4.
Role of p53 in transcriptional repression of SVCT2.
Mol Biol Rep
; 48(2): 1651-1658, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33580460
5.
Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis.
J Biol Chem
; 294(35): 12957-12974, 2019 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296660
6.
Reciprocal negative regulation between the tumor suppressor protein p53 and B cell CLL/lymphoma 6 (BCL6) via control of caspase-1 expression.
J Biol Chem
; 294(1): 299-313, 2019 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30409904
7.
Cell fate decisions by c-Myc depend on ZBTB5 and p53.
Biochem Biophys Res Commun
; 533(4): 1247-1254, 2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051058
8.
Inhibition of JAK1/2 can overcome EGFR-TKI resistance in human NSCLC.
Biochem Biophys Res Commun
; 527(1): 305-310, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446385
9.
Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells.
Invest New Drugs
; 38(6): 1696-1706, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32462369
10.
Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.
Biochim Biophys Acta
; 1859(11): 1429-1439, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27646874
11.
ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65.
Nucleic Acids Res
; 43(3): 1609-25, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25609694
12.
KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes.
Proc Natl Acad Sci U S A
; 111(42): 15078-83, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288747
13.
Transcriptional activation of APAF1 by KAISO (ZBTB33) and p53 is attenuated by RelA/p65.
Biochim Biophys Acta
; 1849(9): 1170-8, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26183023
14.
Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.
Nucleic Acids Res
; 42(18): 11447-61, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25245946
15.
Promyelocytic leukemia zinc finger-retinoic acid receptor α (PLZF-RARα), an oncogenic transcriptional repressor of cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) and tumor protein p53 (TP53) genes.
J Biol Chem
; 289(27): 18641-56, 2014 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24821728
16.
Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene.
J Biol Chem
; 289(7): 4018-31, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24382891
17.
Role of promyelocytic leukemia zinc finger (PLZF) in cell proliferation and cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) gene repression.
J Biol Chem
; 289(27): 18625-40, 2014 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24821727
18.
The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.
Nucleic Acids Res
; 41(13): 6403-20, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23658227
19.
Regulation of the cyclin-dependent kinase inhibitor 1A gene (CDKN1A) by the repressor BOZF1 through inhibition of p53 acetylation and transcription factor Sp1 binding.
J Biol Chem
; 288(10): 7053-64, 2013 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23329847
20.
The Immune Suppressor IGSF1 as a Potential Target for Cancer Immunotherapy.
Cancer Immunol Res
; 12(4): 491-507, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38289363