Detalhe da pesquisa
1.
Olaparib for Metastatic Castration-Resistant Prostate Cancer.
N Engl J Med
; 382(22): 2091-2102, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32343890
2.
A comparative study of germline BRCA1 and BRCA2 mutation screening methods in use in 20 European clinical diagnostic laboratories.
Br J Cancer
; 117(5): 710-716, 2017 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28751759
3.
Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.
Br J Cancer
; 117(2): 256-265, 2017 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28557976
4.
Selumetinib Plus Docetaxel Compared With Docetaxel Alone and Progression-Free Survival in Patients With KRAS-Mutant Advanced Non-Small Cell Lung Cancer: The SELECT-1 Randomized Clinical Trial.
JAMA
; 317(18): 1844-1853, 2017 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28492898
5.
TP53 mutations occur in 15.7% of ALL and are associated with MYC-rearrangement, low hypodiploidy, and a poor prognosis.
Blood
; 124(2): 251-8, 2014 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24829203
6.
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.
Blood
; 123(6): 894-904, 2014 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24363398
7.
Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.
Blood
; 123(14): 2229-37, 2014 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24523240
8.
Comprehensive mutational profiling in advanced systemic mastocytosis.
Blood
; 122(14): 2460-6, 2013 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23958953
9.
Unraveling the complexity of tyrosine kinase inhibitor-resistant populations by ultra-deep sequencing of the BCR-ABL kinase domain.
Blood
; 122(9): 1634-48, 2013 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23794064
10.
EZH2 mutations are frequent and represent an early event in follicular lymphoma.
Blood
; 122(18): 3165-8, 2013 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24052547
11.
Association of the type of 5q loss with complex karyotype, clonal evolution, TP53 mutation status, and prognosis in acute myeloid leukemia and myelodysplastic syndrome.
Genes Chromosomes Cancer
; 53(5): 402-10, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24493299
12.
Acute lymphoblastic leukemia with low hypodiploid/near triploid karyotype is a specific clinical entity and exhibits a very high TP53 mutation frequency of 93%.
Genes Chromosomes Cancer
; 53(6): 524-36, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24619868
13.
Subnetwork-based analysis of chronic lymphocytic leukemia identifies pathways that associate with disease progression.
Blood
; 120(13): 2639-49, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837534
14.
Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity.
Blood
; 119(20): 4719-22, 2012 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22442349
15.
SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML).
Blood
; 120(15): 3080-8, 2012 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22919025
16.
A novel hierarchical prognostic model of AML solely based on molecular mutations.
Blood
; 120(15): 2963-72, 2012 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22915647
17.
Postallogeneic monitoring with molecular markers detected by pretransplant next-generation or Sanger sequencing predicts clinical relapse in patients with myelodysplastic/myeloproliferative neoplasms.
Eur J Haematol
; 92(3): 189-94, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24164563
18.
The molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL.
Genes Chromosomes Cancer
; 52(4): 410-22, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23341344
19.
Pan-Tumor Analytical Validation and Osimertinib Clinical Validation in EGFR Mutant Non-Small-Cell Lung Cancer, Supporting the First Next-Generation Sequencing Liquid Biopsy in Vitro Diagnostic.
J Mol Diagn
; 26(1): 73-84, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37981090
20.
Performance characteristics of a polymerase chain reaction-based assay for the detection of EGFR mutations in plasma cell-free DNA from patients with non-small cell lung cancer using cell-free DNA collection tubes.
PLoS One
; 19(4): e0295987, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593164