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1.
J Pediatr Surg ; 2024 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-38806318

RESUMO

The American Pediatric Surgical Association (APSA) Practice Committee endorsed by the Board of Governors presents a Position Statement on the role of locum tenens in the practice of pediatric surgery. The Practice Committee also presents a set of guidelines for locum tenens practice. These recommendations highlight safe practice and quality care that protects the patient as well as the pediatric surgeon by offering best practice standards, defining optimal resources and establishing parameters by which hospitals and locum tenens agencies should abide. These guidelines are intended to foster discussion and contract negotiation as well as inform decision making for a) pediatric surgeons considering locum tenens opportunities, b) host organizations (hospitals and practices) seeking the coverage of a pediatric surgeon, and c) locum tenens companies vetting both surgeons and hospitals for appropriateness of such coverage. This Position Statement and foundational set of guidelines align with APSA's Vision (all children receive the highest quality surgical care) and Mission (to provide the best surgical care to our patients and families by supporting an inclusive community through education, discovery and advocacy).

2.
JSLS ; 14(4): 553-7, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21605521

RESUMO

BACKGROUND: Laparoscopic pyloromyotomy is associated with an increased risk of incomplete myotomy compared with open myotomy. We hypothesized that utilizing ultrasound measured length to direct laparoscopic pyloromyotomy would reduce the risk of incomplete pyloromyotomy without a concomitant increase in the risk of mucosal perforation. METHODS: Infants (n=43) with hypertrophic pyloric stenosis diagnosed by ultrasound and subsequent laparoscopic pyloromyotomy over a 2-year period (December 2006 through December 2008) were studied. Pyloromyotomy length was guided by preoperative ultrasound measurements. Pyloromyotomy was considered complete if the measured length was ≥ the ultrasound measurement. Infants were followed prospectively for time to full feeding, time to discharge, and complications. RESULTS: The cohort included 38 male and 5 female infants (age, 37±13 days; range, 17 to 72 days) who underwent ultrasound (length 1.9±0.2cm; thickness 4.4±0.9mm) and laparoscopic pyloromyotomy. Infants achieved full feeding 28±16 hours postoperatively and were discharged 34±18 hours postoperatively. No infant required reoperation for incomplete myotomy. One infant sustained mucosal perforation (2%). No patient suffered other complications. CONCLUSION: Preoperative ultrasound measurement of pyloric length to determine the length of laparoscopic pyloromyotomy, rather than visual cues alone, appears to minimize the risk of incomplete pyloromyotomy.


Assuntos
Laparoscopia/métodos , Estenose Pilórica Hipertrófica/diagnóstico por imagem , Piloro/cirurgia , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Masculino , Estenose Pilórica Hipertrófica/congênito , Estenose Pilórica Hipertrófica/cirurgia , Piloro/diagnóstico por imagem , Estudos Retrospectivos , Resultado do Tratamento , Ultrassonografia
3.
JSLS ; 12(3): 238-40, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18765044

RESUMO

BACKGROUND: Robot-assisted surgery must be evaluated before its acceptance as an option for standard therapy in the pediatric population. Our objective is a comparison of results using the robot system with results for the laparoscopic and open approaches. METHODS: Following IRB approval, robot-assisted procedures were case-matched with controls, selected from 1994 to 2005. Data for 150 Nissen cases were divided equally into 3 groups [robot (R), laparoscopic (L), and open (O)], comparing surgical times, length of hospitalization, and outcomes. RESULTS: The average age (R = 117+/-64 months, L = 107+/-71 months, O = 85+/-55 months, P<0.05) and weight (R = 37+/-23 kg, L = 33+/-24 kg, O = 24+/-17 kg, P<0.05) of the open group were lower comparatively. Robot operative times proved significantly longer compared with laparoscopic and open time (R = 160+/-61 min, L = 107+31 min, O = 73+/-27 min, P<0.05). The robot had 2 conversions (2/50, 4%), comparable to the laparoscopic conversion rate (1/50, 2%). Open cases resulted in longer hospitalization [R = 2.94+/-4.5 days, L = 3.54+/-7.8 days, O = 3.5+/-2.8, P<0.05]. Complication rates were equivalent between groups. The most common complication with the da Vinci and laparoscopic approaches was tight wrap requiring dilation [R = 4/50 (8%) and L = 3/50 (6%)]. CONCLUSION: Robot-assisted surgery is equivalent to standard laparoscopic surgery in terms of complications and length of stay, with both having significantly increased operation times but reduced length of stay compared with open surgery. Further experience with this technology is needed to overcome the learning curve and reduce operative times.


Assuntos
Fundoplicatura/instrumentação , Fundoplicatura/métodos , Laparoscopia/métodos , Robótica/instrumentação , Estudos de Casos e Controles , Criança , Pré-Escolar , Feminino , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Complicações Pós-Operatórias , Fatores de Risco , Resultado do Tratamento
4.
Am J Surg ; 211(3): 605-9, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26778271

RESUMO

BACKGROUND: Current treatment of giant omphalocele includes "paint and wait" or placement of mesh or silo. These methods are associated with high complication rates. We propose negative pressure wound therapy as an alternative. METHODS: Patients born between 2009 and 2014 with giant omphalocele were included. Outcomes analyzed were duration of therapy, time to full enteral feeds, treatment related complications, wound surface area over time, type, and time to definitive closure. RESULTS: Eight patients were reviewed. The median duration of therapy was 68 days. Median time to full enteral feeds was 19 days. There were no treatment discontinuations or complications including sac ruptures, wound infections, or fistulas. Wound contraction stopped at 2 months or around 7 cm(2). All surviving patients underwent definitive closure. CONCLUSIONS: Negative pressure wound therapy is a safe and effective treatment for giant omphalocele that allows feeding, has a low complication rate, and is completed in 2 months.


Assuntos
Hérnia Umbilical/terapia , Tratamento de Ferimentos com Pressão Negativa , Cicatrização/fisiologia , Nutrição Enteral , Feminino , Humanos , Recém-Nascido , Masculino , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento
5.
J Pediatr Surg ; 45(11): 2227-33, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21034949

RESUMO

BACKGROUND/PURPOSE: Although the use of minimally invasive surgical (MIS) techniques for children with cancer is being practiced by some, its role remains unclearly defined. The purpose of this review was to describe the current literature on MIS for thoracic and mediastinal lesions in children. METHODS: We performed a literature search for English studies that evaluated MIS techniques for biopsy or resection in children with suspected or established cancer. Only studies with greater than 20 patients were included in the review. RESULTS: Ten studies were included for review. Each represented institutional retrospective reviews of experience. Seven were single-institution studies, and 3 were multi-institutional. There were no prospective nor randomized identified. CONCLUSIONS: Based on primarily retrospective and observational data, the use of MIS for children with cancer who have pulmonary and mediastinal lesions seems to be effective and safe. Ideally, prospective studies are needed to evaluate this further.


Assuntos
Sociedades Médicas , Neoplasias Torácicas/cirurgia , Cirurgia Torácica Vídeoassistida/métodos , Toracoscópios/normas , Criança , Desenho de Equipamento , Humanos , Cirurgia Torácica Vídeoassistida/normas , Estados Unidos
6.
J Pediatr Surg ; 44(1): 289-93, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19159759

RESUMO

Pediatric empyema can be managed with a variety of modalities, and the evidence for an ideal management strategy is limited. Early or simple effusions can be treated with antibiotics alone or with drainage when respiratory distress occurs. Once fibrinopurulent empyema has developed, therapy may involve either chest tube placement with instillation of fibrinolytics or video-assisted thoracoscopic surgery with pleural decortication. In late or fibrotic empyema, an assumption persists that the fibrotic peel must be managed by decortication that can be done either thoracoscopically or through a minithoracotomy incision. This position paper is coauthored by the New Technology Committee of the American Pediatric Surgery Association. The goal is to discuss the ongoing controversies and summarize, in an evidence-based manner, the various treatment options and to suggest a reasonable therapeutic algorithm for the care of children with empyema.


Assuntos
Empiema Pleural/cirurgia , Cirurgia Torácica Vídeoassistida , Algoritmos , Criança , Empiema Pleural/tratamento farmacológico , Humanos , Terapia Trombolítica
7.
J Pediatr Surg ; 44(1): 169-71; discussion 171-2, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19159738

RESUMO

PURPOSE: We will demonstrate that a surgical resident with proven accuracy in the diagnosis of hypertrophic pyloric stenosis (HPS) can teach other surgeons to diagnose HPS with reproducible accuracy. METHODS: A surgical resident with proven sonographic accuracy in diagnosing HPS instructed 5 other surgical residents in the technique. Consecutive patients referred to pediatric surgery with a presumed clinical diagnosis of HPS were examined, and measurements of residents were compared with formal radiology studies. Each surgeon was proctored for 5 examinations before independent evaluation and was blinded to results from both radiologists and other residents. Results were evaluated using Student's t test; P less than .05 was considered significant. RESULTS: Seventy-one patients were evaluated by 5 surgical residents. Residents were diagnostically accurate in all cases. There was no statistically significant difference between pyloric muscle thickness or channel length measurements obtained by radiology and any of the residents. CONCLUSION: Surgeon-performed ultrasound examination for the diagnosis of HPS is accurate and reproducible through surgeon-to-surgeon instruction on appropriate technique. This skill is a valuable asset in the initial surgical evaluation of any patient with suspected HPS, expediting appropriate management.


Assuntos
Competência Clínica , Estenose Pilórica Hipertrófica/diagnóstico por imagem , Humanos , Internato e Residência , Estudos Prospectivos , Estenose Pilórica Hipertrófica/cirurgia , Reprodutibilidade dos Testes , Ultrassonografia
8.
J Pediatr Surg ; 44(3): 530-3, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19302853

RESUMO

BACKGROUND/PURPOSE: We previously reported that a diet acidified with citric acid effectively reinforces gastric acid protection against bacterial colonization and translocation. In this study, our objective was to examine a biologically acidified formula hypothesized to be more physiologic than formula acidified with free acid. This study was Institutional Animal Care and Use Committee (IACUC) approved and designed to determine whether this diet is better tolerated and equally effective to acidification with citric acid against gut colonization and subsequent bacterial translocation in a premature infant rabbit model. METHODS: A total of 89 rabbit pups born via cesarean delivery 1 day preterm were randomly assigned to 3 feeding groups: Pelargon Nestle at pH 4.55; NAN Nestle, a control diet at pH 7.0 with similar composition; and NAN Nestle acidified in the laboratory with citric acid at pH 4.55. Pups were gavage fed every 12 hours with Enterobacter cloacae challenges of 10 colony-forming units per milliliter of diet per feed and killed on day 3 of life. Lungs, liver, spleen, mesenteric lymph nodes, stomach, and cecum were cultured and quantitatively analyzed for target organism growth and statistically analyzed using chi(2) and Kruskal-Wallis tests. RESULTS: Pelargon, compared to acidified NAN and NAN, significantly reduced the incidence of gastric colonization (15/33 [45%], 21/27 [78%], and 25/29 [86%], respectively; P < .01) and pulmonary colonization (10/33 [30%], 19/27 [70%], 21/29 [72%]; P < .01). Comparing the bacterial logs of colonized groups, the same benefit is observed in the lungs (0.77 +/- 1.22, 1.89 +/- 1.41, 2.12 +/- 1.47; P < .01). Gut colonization and bacterial translocation were equivalent between treatment groups (mesenteric lymph nodes: 10/33 [30%], 11/27 [40%], 8/29 [27%]; spleen: 10/33 [30%], 7/27 [26%], 8/29 [27%]; liver: 10/33 [30%], 6/27 [22%], 9/29 [31%]; cecum: 33/33 [100%], 27/27 [100%], 29/29 [100%]). CONCLUSION: Biologically acidified formula demonstrated superior protection against pulmonary and gastric colonization compared to normal pH and diets acidified with free acid. Its effects may potentially reduce clinical pulmonary infection.


Assuntos
Translocação Bacteriana/fisiologia , Dieta , Mucosa Gástrica/microbiologia , Pulmão/microbiologia , Probióticos/farmacologia , Animais , Animais Recém-Nascidos , Ceco/microbiologia , Concentração de Íons de Hidrogênio , Mucosa Intestinal/microbiologia , Fígado/microbiologia , Linfonodos/microbiologia , Modelos Animais , Coelhos , Baço/microbiologia , Estômago/microbiologia
9.
J Pediatr Surg ; 44(11): 2130-2, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19944221

RESUMO

PURPOSE: Contrast enema is the initial study of choice for simple meconium ileus to confirm diagnosis and to relieve obstruction. Despite favorable historically published results, our clinical impression suggests decreased effectiveness of the contrast enema resulting in more surgical interventions in contemporary practice. METHODS: A retrospective multiinstitutional review for a 12-year period was conducted for neonates diagnosed with meconium ileus by contrast enema. The neonates were divided into 2 groups-historic group (HG = before 2002) and contemporary group (CG = after 2002). T test was used for comparison of continuous variables and chi(2) for categorical data. RESULTS: Thirty-seven total patients were identified (21 females and 16 males). Obstruction was relieved in 8 neonates (22% overall success rate). Average enema attempt per patient was decreased in the CG group compared to HG (1.4 vs 1.9). The success rate in the CG group was 5.5% (1/18) compared to 39% (7/18) in HG. CONCLUSIONS: In this review, success of contrast enema for relief of meconium ileus has significantly decreased over time. These findings may be because of reluctance to repeat enemas, change in radiologist experience, or use of contrast agent. As a result, higher rates of operative intervention are now observed. In stable patients, surgeons should recommend repeat enemas before exploration.


Assuntos
Fibrose Cística/complicações , Enema/métodos , Íleus/diagnóstico por imagem , Íleus/terapia , Mecônio/diagnóstico por imagem , Peso ao Nascer , Fibrose Cística/cirurgia , Diatrizoato de Meglumina , Enema/estatística & dados numéricos , Feminino , Idade Gestacional , Humanos , Íleus/cirurgia , Recém-Nascido , Masculino , Cuidados Pré-Operatórios/métodos , Radiografia , Estudos Retrospectivos , Resultado do Tratamento
10.
J Pediatr Surg ; 44(6): 1189-92; discussion 1192, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19524738

RESUMO

BACKGROUND: The diagnosis of pyloric stenosis (PS) by physical examination is a lost art that has been replaced by radiology-performed ultrasound (US). The purpose of this study is to demonstrate that the diagnosis of PS can be made solely upon the surgeons US evaluation. METHODS: Surgical ultrasonographers included 2 senior general surgery residents and 2 pediatric surgery residents without prior formal US experience. These surgeons underwent proctored training in the use of US for PS. Measurements including channel length and muscle thickness were recorded at bedside. A positive examination included muscle thickness more than 4 mm and channel length more than 16 mm. Patients with positive results underwent pyloromyotomy. Negative results were confirmed with a repeat US through the radiology department, and infants without PS were subsequently referred for appropriate medical management. RESULTS: Thirty-two consecutive patients with suspected PS were evaluated using surgeon-performed ultrasonography. All examinations were diagnostically accurate. There were no false-positive or false-negative result. Seven patients (22%) were correctly determined to be negative for PS. The remaining 25 infants underwent successful pyloromyotomy with resolution of symptoms. CONCLUSION: Surgeons who have undergone focused training to perform US for PS can diagnose the condition without confirmatory testing by a radiologist.


Assuntos
Papel do Médico , Estenose Pilórica/diagnóstico , Estenose Pilórica/cirurgia , Cirurgia Geral , Humanos , Lactente , Exame Físico , Estenose Pilórica/diagnóstico por imagem , Ultrassonografia
11.
J Pediatr Surg ; 43(1): 83-6, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18206461

RESUMO

BACKGROUND/PURPOSE: At our institution, patients undergoing selected operative procedures are referred to a protocol for telephone follow-up by surgical specialty nurses. Our objective was to review our experience with this protocol to determine if telephone follow-up is a safe and preferred alternative to the traditional postoperative clinic visit. METHODS: Records of patients followed up by telephone over 6 months were evaluated for information regarding each patient's postoperative course. Records included telephone follow-up forms, clinic notes, and emergency department records. RESULTS: A total of 563 patients underwent a total of 601 procedures. Seventy-six percent (n = 427) were successfully contacted postoperatively; 24% (n = 136) did not respond to multiple contact attempts. Forty-five requests for clinic follow-up resulted in 27 actual visits, 10 from families not satisfied with telephone contact alone. Most families contacted (382/427, 90%) were satisfied and did not request an appointment. A total of 43 postoperative clinic or emergency department evaluations resulted in 9 interventions (1.6% complication rate). CONCLUSION: Postoperative follow-up by telephone using a structured protocol is a safe alternative to routine clinic follow-up for patients undergoing selected procedures and is preferred by patients' families.


Assuntos
Assistência ao Convalescente/métodos , Procedimentos Cirúrgicos Operatórios/métodos , Telefone , Adolescente , Criança , Pré-Escolar , Estudos de Coortes , Feminino , Seguimentos , Hospitais Pediátricos , Humanos , Masculino , Papel do Profissional de Enfermagem , Cuidados Pós-Operatórios/métodos , Segurança , Sensibilidade e Especificidade , Fatores de Tempo
12.
J Pediatr Surg ; 43(1): 87-91; discussion 91, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18206462

RESUMO

PURPOSE: The purpose of the study was to validate surgeon-performed abdominal ultrasound in the diagnosis of pyloric stenosis, thus expediting diagnosis and management and increasing overall cost-effectiveness. METHODS: A surgical resident, after completing ultrasound courses offered by the American College of Surgeons, Chicago, IL, examined 30 consecutive patients with a suspected diagnosis of hypertrophic pyloric stenosis (HPS). Blinded regarding both clinical and radiographic findings, the resident scanned the pylorus in longitudinal and transverse axes. Positive ultrasonographic evidence of HPS was defined as muscle thickness of at least 4 mm and/or channel length of at least 16 mm. Surgeon and radiology measurements were compared using descriptive analyses and Student t test. RESULTS: There were 25 boys and 5 girls examined. Twenty-eight of 30 patients were found to have HPS. When ultrasound performed by the surgeon was compared with that of radiology, no false-negative or false-positive results were noted. The surgeon was diagnostically accurate in all cases, and there was no statistically significant difference between surgeon and radiology measurements with regard to pyloric muscle thickness (P = .825, mean deviation = 0.4 mm) or channel length (P = .74, mean deviation = 2.2 mm). CONCLUSION: A surgeon with appropriate training in abdominal ultrasound can diagnose HPS with the same degree of accuracy as radiologists.


Assuntos
Endossonografia/métodos , Estenose Pilórica/diagnóstico por imagem , Estenose Pilórica/cirurgia , Estudos de Coortes , Feminino , Humanos , Lactente , Masculino , Papel do Médico , Radiografia Abdominal/métodos , Valores de Referência , Sensibilidade e Especificidade , Índice de Gravidade de Doença
13.
J Pediatr Surg ; 43(7): 1338-41, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18639692

RESUMO

PURPOSE: Evidence-based guidelines for the treatment of pediatric snakebite injuries are lacking because they occur infrequently in most centers. METHODS: We reviewed our experience treating snakebites from January 1995 through December 2005. Demographic (eg, age, sex, geographic location) and clinical information (eg, location of bite, species of snake, vital signs, laboratories, treatment, hospital length of stay) were obtained. RESULTS: Over the last decade, we have treated 114 children with confirmed snakebites. Mean age was 7.3 +/- 4.2 years (range, 1-17 years), and snakebites were more common in males (n = 68, 60%). All bites occurred on the extremities, and lower extremity bites were more common (n = 71, 62%). Copperheads inflicted the most bite injuries (n = 65, 57%), followed by rattlesnakes (n = 9, 8%) and cottonmouths (n = 7, 6%). The snake was not identified in 33 (29%) cases. Seven (6%) children were treated with Crotalidae antivenin. Of the children treated with antivenin, only 4 met criteria for treatment, and 1 had an anaphylactic reaction. If compartment syndrome was suspected based on neurovascular examination, compartment pressures were measured. Only 2 (1.8%) patients required fasciotomies. Over the last 2 years, we have stopped empiric treatment with antibiotics and have not observed any infectious complications. Average hospital length of stay was 30 +/- 25 hours. CONCLUSIONS: Most children bitten by pit vipers can be managed conservatively with analgesics and elevation of the affected extremity. Treatment with Crotalidae antivenin, antibiotics, and fasciotomy is rarely indicated.


Assuntos
Mordeduras de Serpentes/terapia , Adolescente , Arkansas , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Estudos Retrospectivos , Mordeduras de Serpentes/tratamento farmacológico , Mordeduras de Serpentes/cirurgia
14.
J Pediatr Surg ; 43(6): 1072-6, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-18558185

RESUMO

PURPOSE: Current organizational guidelines for the management of isolated spleen and liver injuries are based on injury grade. We propose that management based on hemodynamic status is safe in children and results in decreased length of stay (LOS) and resource use compared to current grade-based guidelines. METHODS: Patients with spleen or liver injuries for a 5-year period were identified using our institutional trauma registry. All patients were managed using a pathway based on hemodynamic status. Charts were reviewed for demographics, mechanism, hematrocrit values, transfusion requirement, imaging, injury grade, LOS, and outcome. Exclusion criteria included penetrating mechanism, associated injuries altering LOS or ambulation status, combined spleen/liver injury, initial operative management or death. Statistical comparison was performed using Student's t test; P < .05 is significant. RESULTS: One hundred one patients (50 spleen, 51 liver) meeting inclusion criteria were identified. Average actual LOS for all patients was 1.9 days vs 3.2 projected days based on American Pediatric Surgical Association guidelines (P < .0001). Actual vs projected LOS for grades III to V was 2.5 vs 4.3 days (P < .0001). All patients returned to full activity without complication. CONCLUSIONS: Isolated blunt spleen and liver injuries, regardless of grade, can be safely managed using a pathway based on hemodynamic status, resulting in decreased LOS and resource use compared to current guidelines.


Assuntos
Hemodinâmica/fisiologia , Fígado/lesões , Traumatismo Múltiplo/terapia , Baço/lesões , Ferimentos não Penetrantes/terapia , Distribuição por Idade , Criança , Pré-Escolar , Estudos de Coortes , Feminino , Seguimentos , Humanos , Incidência , Lactente , Escala de Gravidade do Ferimento , Tempo de Internação , Masculino , Traumatismo Múltiplo/diagnóstico , Guias de Prática Clínica como Assunto , Probabilidade , Sistema de Registros , Medição de Risco , Distribuição por Sexo , Resultado do Tratamento , Ferimentos não Penetrantes/diagnóstico , Ferimentos não Penetrantes/epidemiologia
15.
J Pediatr Surg ; 43(1): 25-9; discussion 29, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18206450

RESUMO

BACKGROUND/PURPOSE: Acidified diets are protective against intestinal bacterial colonization and translocation. Probiotic diets are designed to modulate the intestinal flora to enhance mucosal immunity. This study was designed to determine if formula acidified with live probiotic decreases bacterial gut colonization and translocation, and is equally tolerated as other acidified diets. METHODS: One hundred twenty-eight rabbit pups delivered via cesarean section [cesarean delivery, cesarean birth, abdominal delivery] were randomly assigned to 4 feeding groups: NAN Nestle (control, pH 7.0), NAN acidified with citric acid (pH 4.55), biologically acidified Pelargon (pH 4.55), and NAN with live Lactococcus lactis culture (pH 4.2). Pups were gavage fed every 12 hours with Enterobacter cloacae challenges of 10 colony-forming units/mL per feed and killed on day of life 3. Lungs, liver, spleen, mesenteric lymph nodes (MLNs), stomach, and cecum were cultured and quantitatively analyzed for target organism growth. Results were analyzed using chi(2) tests. RESULTS: NAN with live probiotic culture, when compared with Pelargon, acidified NAN, and NAN, significantly reduced the incidence of Enterobacter pulmonary colonization (P < .01), bacterial translocation (liver, P < .025; spleen and MLN, P < .05), and gastric and intestinal colonization (P < .001 for both). CONCLUSION: Probiotic-fortified formula provides superior protection against pulmonary and gastrointestinal bacterial colonization and translocation compared with neutral and acidified formulas, and is equally tolerated.


Assuntos
Animais Recém-Nascidos , Translocação Bacteriana/fisiologia , Alimentos Formulados , Gastroenteropatias/microbiologia , Pulmão/microbiologia , Probióticos/farmacologia , Animais , Translocação Bacteriana/efeitos dos fármacos , Contagem de Colônia Microbiana , Modelos Animais de Doenças , Nutrição Enteral/métodos , Enterocolite Necrosante/prevenção & controle , Feminino , Mucosa Gástrica/microbiologia , Mucosa Gástrica/patologia , Mucosa Intestinal/microbiologia , Mucosa Intestinal/patologia , Masculino , Probabilidade , Coelhos , Distribuição Aleatória , Valores de Referência , Medição de Risco , Sensibilidade e Especificidade
16.
J Pediatr Surg ; 43(12): 2256-9, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19040947

RESUMO

BACKGROUND/PURPOSE: Secure placement of peritoneal dialysis (PD) catheters in the pelvis has been described by various techniques. We describe minimally invasive placement using an Endo Close device, securing the catheter in the pelvis, and compare this method with standard open technique in children. METHODS: A retrospective institutional review was conducted for children requiring PD access from 2001 to 2007. Patients were grouped into laparoscopic with secure placement (SP) and open placement (OP) groups. Groups were cohort-matched based on age, paying particular attention to the number of catheter migrations. RESULTS: Twenty-seven patients underwent 36 procedures in SP, whereas 23 patients in OP had 32 catheter-related procedures. Exit site infections were decreased in SP (0.57 vs 1.33 episodes per patient-year). There was no difference in the number of catheter migrations (3 vs 5); however, time to migration was statistically longer in the SP group (9 vs. 2.4 months, P < .05). CONCLUSIONS: Laparoscopic placement of PD catheters using a securing suture in the pelvis is a more durable technique when compared to open placement. Extending the catheter migration time is important in children when PD is used as a bridge to renal transplantation.


Assuntos
Cateterismo/métodos , Laparoscopia/métodos , Diálise Peritoneal/instrumentação , Técnicas de Sutura , Adolescente , Cateterismo/efeitos adversos , Criança , Pré-Escolar , Feminino , Migração de Corpo Estranho/epidemiologia , Migração de Corpo Estranho/etiologia , Humanos , Falência Renal Crônica/terapia , Laparoscopia/estatística & dados numéricos , Laparotomia/estatística & dados numéricos , Masculino , Pelve , Diálise Peritoneal/efeitos adversos , Peritonite/epidemiologia , Peritonite/etiologia , Reoperação , Estudos Retrospectivos
17.
Pediatr Dev Pathol ; 10(6): 470-6, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18001156

RESUMO

Hajdu-Cheney syndrome is a rare disorder characterized by short stature, joint hypermobility, distinctive craniofacial and skull abnormalities, dental anomalies, and acroosteolysis of the distal phalanges. Cystic kidneys have been associated with some cases. We report a case of a 12-year-old girl with renal failure who underwent bilateral nephrectomies. Histopathological examination revealed polycystic kidneys with numerous nodules located throughout the kidney composed of basaloid epithelial cells.


Assuntos
Síndrome de Hajdu-Cheney/patologia , Doenças Renais Policísticas/patologia , Insuficiência Renal/patologia , Criança , Feminino , Síndrome de Hajdu-Cheney/complicações , Síndrome de Hajdu-Cheney/cirurgia , Humanos , Nefrectomia , Doenças Renais Policísticas/etiologia , Doenças Renais Policísticas/cirurgia , Insuficiência Renal/etiologia , Insuficiência Renal/cirurgia
18.
Am J Surg ; 194(6): 712-7; discussion 718-9, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18005759

RESUMO

BACKGROUND: Management of typical malrotation is universally accepted, but management of atypical malrotation is less well defined in both children and adults. METHODS: Records of patients with malrotation diagnosed over 6 years were reviewed. Patients were grouped into typical or atypical based on ligament of Treitz location. Outcomes were evaluated using chi-square analysis. RESULTS: Of 275 patients, 148 diagnosed with typical malrotation underwent Ladd's procedure. Based on symptoms, 91 of 127 patients with atypical malrotation were managed operatively. The remaining 36 patients were asymptomatic or had reflux symptoms only and were observed. Six of 36 subsequently required surgery due to symptoms, but 30 remain asymptomatic. No observed patients developed acute midgut volvulus. The overall postoperative complication rates were higher for atypical versus typical malrotation, 27% versus 16% (P < .05). CONCLUSIONS: Close observation with repeat contrast study is an acceptable management option for patients with atypical malrotation who are asymptomatic or exhibit only reflux symptoms.


Assuntos
Obstrução Intestinal/diagnóstico , Obstrução Intestinal/cirurgia , Adolescente , Adulto , Algoritmos , Distribuição de Qui-Quadrado , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Obstrução Intestinal/etiologia , Volvo Intestinal , Laparoscopia , Masculino , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Resultado do Tratamento
19.
Ann Thorac Surg ; 84(5): 1746-8, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17954104

RESUMO

A neonate was diagnosed with hypoplastic left heart syndrome, heterotaxy syndrome, and interrupted inferior vena cava soon after birth. At 6 days old she underwent the Norwood procedure using Sano modification. Postoperatively she had persistent direct hyperbilirubinemia and was diagnosed with biliary atresia for which she underwent a Kasai procedure at 29 days old. At 10 months she underwent the Kawashima procedure. She is now 20 months old and has been thriving without any jaundice. This case report illustrates that even in the presence of major multiple congenital anomalies, staged reconstruction for hypoplastic left heart syndrome can be successfully performed.


Assuntos
Anormalidades Múltiplas/cirurgia , Atresia Biliar/cirurgia , Síndrome do Coração Esquerdo Hipoplásico/cirurgia , Veia Cava Inferior/anormalidades , Procedimentos Cirúrgicos Cardíacos , Feminino , Técnica de Fontan , Humanos , Lactente
20.
J Surg Res ; 137(1): 83-8, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17109888

RESUMO

BACKGROUND: Our objective was to compare the racial differences in incidence and management of pediatric appendicitis. MATERIALS AND METHODS: Data for this study come from two large national hospital discharge databases from the Agency for Healthcare Research and Quality Healthcare Costs and Utilization Project: The Nationwide Inpatient Sample (NIS) and the Kids' Inpatient Database (KID). Analysis was restricted to age less than 18 years with an ICD-9 diagnosis of either simple (540.9) or complex (540.0 and 540.1) appendicitis. Data were weighted to represent national estimates. Incidence was defined as the number of new disease cases divided by the number of at risk hospitalized children. RESULTS: The data for this study contained an estimated 428,463 [95% confidence interval (CI) = 414, 672-442, 253] cases of appendicitis, representing approximately 65,000 to 75,000 cases annually. Multi-variant analysis suggests that African-Americans, as compared to Caucasians, were less prone to develop appendicitis [odds ratio (OR) = 0.39, 95% CI (0.38, 0.41)], but less frequently underwent laparoscopic treatment [OR = 0.78, 95% CI (0.74, 0.87)], and were more likely to have complex appendicitis [OR = 1.39, 95% CI (1.30, 1.49)]. In contrast, Hispanics were more likely than Caucasians to both develop appendicitis [OR = 1.48, 95% CI (1.41, 1.56)] and to have complex disease [OR = 1.10, 95% CI (1.05, 1.16)]. The incidence of appendicitis was less frequent in females versus males [OR = 0.69, 95% CI (0.68, 0.70)] but the likelihood of laparoscopic exploration was higher [OR = 1.39, 95% CI (1.34, 1.43)]. Finally, children with public insurance [OR = 1.25, 95% CI (1.21, 1.29)] and uninsured children [OR = 1.10, 95% CI (1.04, 1.16)] were more likely to have complex appendicitis when compared to children with private insurance. CONCLUSIONS: African-American children with appendicitis have lower overall hospitalization rates, higher rates of perforation, a greater delay to surgical management, and lower laparoscopic rates. In contrast, Hispanic children more frequently had appendicitis and complex disease. The treatment of African-American and Hispanic children overall was associated with a longer hospital stay and higher charges. The lower incidence of appendicitis in African-American children is incompletely understood and the disparity in surgical management among minority children remains troubling.


Assuntos
Apendicite/etnologia , Negro ou Afro-Americano/estatística & dados numéricos , Hispânico ou Latino/estatística & dados numéricos , Perfuração Intestinal/etnologia , População Branca/estatística & dados numéricos , Adolescente , Apendicite/mortalidade , Apendicite/cirurgia , Criança , Pré-Escolar , Bases de Dados Factuais/estatística & dados numéricos , Feminino , Humanos , Incidência , Lactente , Seguro Saúde/estatística & dados numéricos , Perfuração Intestinal/mortalidade , Perfuração Intestinal/cirurgia , Laparoscopia/estatística & dados numéricos , Tempo de Internação/estatística & dados numéricos , Masculino , Razão de Chances , Estados Unidos/epidemiologia
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