Detalhe da pesquisa
1.
Human glioma cell sensitivity to the sequence-specific alkylating agent methyl-lexitropsin.
Clin Cancer Res
; 13(2 Pt 1): 612-20, 2007 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17255284
2.
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
Clin Cancer Res
; 8(9): 3008-18, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12231548
3.
Apurinic endonuclease activity in adult gliomas and time to tumor progression after alkylating agent-based chemotherapy and after radiotherapy.
Clin Cancer Res
; 10(23): 7875-83, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15585620
4.
O6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma.
BBA Clin
; 3: 1-10, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25558448
5.
Repair of 3-methyladenine and abasic sites by base excision repair mediates glioblastoma resistance to temozolomide.
Front Oncol
; 2: 176, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23230562
6.
Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
Mol Cancer Ther
; 9(5): 1208-18, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20457618