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1.
Phys Rev Lett ; 130(11): 111801, 2023 Mar 17.
Artigo em Inglês | MEDLINE | ID: mdl-37001070

RESUMO

We present the first search for the pair production of dark particles X via K_{L}^{0}→XX with X decaying into two photons using the data collected by the KOTO experiment. No signal was observed in the mass range of 40-110 MeV/c^{2} and 210-240 MeV/c^{2}. This sets upper limits on the branching fractions as B(K_{L}^{0}→XX)<(1-4)×10^{-7} and B(K_{L}^{0}→XX)<(1-2)×10^{-6} at the 90% confidence level for the two mass regions, respectively.

2.
Phys Rev Lett ; 129(21): 212502, 2022 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-36461972

RESUMO

The new isotope ^{39}Na, the most neutron-rich sodium nucleus observed so far, was discovered at the RIKEN Nishina Center Radioactive Isotope Beam Factory using the projectile fragmentation of an intense ^{48}Ca beam at 345 MeV/nucleon on a beryllium target. Projectile fragments were separated and identified in flight with the large-acceptance two-stage separator BigRIPS. Nine ^{39}Na events have been unambiguously observed in this work and clearly establish the particle stability of ^{39}Na. Furthermore, the lack of observation of ^{35,36}Ne isotopes in this experiment significantly improves the overall confidence that ^{34}Ne is the neutron dripline nucleus of neon. These results provide new key information to understand nuclear binding and nuclear structure under extremely neutron-rich conditions. The newly established stability of ^{39}Na has a significant impact on nuclear models and theories predicting the neutron dripline and also provides a key to understanding the nuclear shell property of ^{39}Na at the neutron number N=28, which is normally a magic number.

3.
Phys Rev Lett ; 126(12): 121801, 2021 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-33834796

RESUMO

The rare decay K_{L}→π^{0}νν[over ¯] was studied with the dataset taken at the J-PARC KOTO experiment in 2016, 2017, and 2018. With a single event sensitivity of (7.20±0.05_{stat}±0.66_{syst})×10^{-10}, three candidate events were observed in the signal region. After unveiling them, contaminations from K^{±} and scattered K_{L} decays were studied, and the total number of background events was estimated to be 1.22±0.26. We conclude that the number of observed events is statistically consistent with the background expectation. For this dataset, we set an upper limit of 4.9×10^{-9} on the branching fraction of K_{L}→π^{0}νν[over ¯] at the 90% confidence level.

4.
Phys Rev Lett ; 122(2): 021802, 2019 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-30720307

RESUMO

A search for the rare decay K_{L}→π^{0}νν[over ¯] was performed. With the data collected in 2015, corresponding to 2.2×10^{19} protons on target, a single event sensitivity of (1.30±0.01_{stat}±0.14_{syst})×10^{-9} was achieved and no candidate events were observed. We set an upper limit of 3.0×10^{-9} for the branching fraction of K_{L}→π^{0}νν[over ¯] at the 90% confidence level (C.L.), which improved the previous limit by almost an order of magnitude. An upper limit for K_{L}→π^{0}X^{0} was also set as 2.4×10^{-9} at the 90% C.L., where X^{0} is an invisible boson with a mass of 135 MeV/c^{2}.

5.
Phys Rev Lett ; 121(2): 022501, 2018 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-30085743

RESUMO

The discovery of the important neutron-rich nucleus _{20}^{60}Ca_{40} and seven others near the limits of nuclear stability is reported from the fragmentation of a 345 MeV/u ^{70}Zn projectile beam on ^{9}Be targets at the radioactive ion-beam factory of the RIKEN Nishina Center. The produced fragments were analyzed and unambiguously identified using the BigRIPS two-stage in-flight separator. The eight new neutron-rich nuclei discovered, ^{47}P, ^{49}S, ^{52}Cl, ^{54}Ar, ^{57}K, ^{59,60}Ca, and ^{62}Sc, are the most neutron-rich isotopes of the respective elements. In addition, one event consistent with ^{59}K was registered. The results are compared with the drip lines predicted by a variety of mass models and it is found that the models in best agreement with the observed limits of existence in the explored region tend to predict the even-mass Ca isotopes to be bound out to at least ^{70}Ca.

6.
Phys Rev Lett ; 113(26): 262502, 2014 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-25615314

RESUMO

Excited states in the N=102 isotones 166Gd and 164Sm have been observed following isomeric decay for the first time at RIBF, RIKEN. The half-lives of the isomeric states have been measured to be 950(60) and 600(140) ns for 166Gd and 164Sm, respectively. Based on the decay patterns and potential energy surface calculations, including ß6 deformation, a spin and parity of 6- has been assigned to the isomeric states in both nuclei. Collective observables are discussed in light of the systematics of the region, giving insight into nuclear shape evolution. The decrease in the ground-band energies of 166Gd and 164Sm (N=102) compared to 164Gd and 162Sm (N=100), respectively, presents evidence for the predicted deformed shell closure at N=100.

7.
Biochim Biophys Acta ; 1226(2): 201-5, 1994 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-8204668

RESUMO

Enzyme activity, protein contents, and mRNA contents of group II phospholipase A2 (PLA2) in hepatocellular carcinoma (HCC) surgically obtained from 8 patients were compared with those in either its neighboring liver tissues or control liver tissues. The PLA2 specific activity towards the mixed micelles of 1-palmitoyl-2-oleoyl-phosphatidylglycerol and cholate was significantly greater in the tumor tissues (6.62 +/- 1.46 nmol/min/mg) than those in the surrounding liver tissues (1.33 +/- 0.22 nmol/min/mg) and controls (0.43 +/- 0.04 nmol/min/mg). The results of immunoblot analysis using a specific anti-human group II PLA2 antibody and of Northern blot analysis using a human group II PLA2 cDNA as a probe demonstrated that group II PLA2 was responsible for the increased enzyme activity. The contents of immunoreactive group II PLA2 in the tumor tissues (8.81 +/- 1.24 ng/mg) were significantly higher than those in the surrounding liver tissues (1.74 +/- 0.27 ng/mg); those in the control tissues were below the analytical range of the method used. The group II PLA2 mRNA was also significantly increased in the tumor tissues, compared with that in the surrounding liver tissues, whereas it was not detectable in the controls. This indicates that group II PLA2 in HCC is induced at the pretranslational level.


Assuntos
Carcinoma Hepatocelular/enzimologia , Neoplasias Hepáticas/enzimologia , Fosfolipases A/genética , Expressão Gênica , Humanos , Fígado/enzimologia , Fosfolipases A2 , RNA Mensageiro/análise
8.
FEBS Lett ; 304(1): 69-72, 1992 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-1618301

RESUMO

Previously, we reported the presence of group II-like phospholipase A2 activity in the soluble fraction of rat gingiva. In the present study, we found that treatment of rat gingival cells with human recombinant interleukin-1 beta resulted in dose-dependent stimulation of intracellular and extracellular phospholipase A2 activity. Antisera against group II phospholipase A2 totally blocked the interleukin-1 beta-induced phospholipase A2 activity, but antisera against group I phospholipase A2 did not. Moreover, immunoblot analysis showed that the induced phospholipase A2 was group II phospholipase A2. These findings suggest that the induced enzyme belongs to the group II phospholipase A2 family of proinflammatory enzymes.


Assuntos
Gengiva/enzimologia , Interleucina-1/fisiologia , Fosfolipases A/biossíntese , Animais , Células Cultivadas , Indução Enzimática , Fibroblastos/enzimologia , Gengiva/citologia , Immunoblotting , Cinética , Masculino , Fosfolipases A2 , Ratos , Ratos Endogâmicos
9.
Acta Crystallogr B ; 55(Pt 1): 31-34, 1999 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-10927336

RESUMO

By using the X-ray diffraction technique, residual short-range order was detected in CeInCu(2), cerium dicopper indium, which is known to be a heavy fermion compound. In spite of the long-range order of this substance, diffuse scattering exhibiting short-range order was observed at room temperature. The correlation parameters obtained showed that an incorrectly occupied lattice site has a tendency to gather atoms of different species at the neighboring sites along the <111> directions. Thus, the disordered region would form a cluster composed of several disordered atoms. Furthermore, a chain-type correlation which has a period of 20-23 Å along the same directions was indicated. The superstructure-like feature of the disordered atoms hardly increases the residual resistivity. It is consistent with the behavior of the residual resistivity under high pressure.

16.
Phys Rev B Condens Matter ; 35(16): 8873-8875, 1987 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-9941279
17.
Phys Rev B Condens Matter ; 37(17): 10357-10360, 1988 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-9944473
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