Detalhe da pesquisa
1.
Structural Basis for Shelterin Bridge Assembly.
Mol Cell
; 68(4): 698-714.e5, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149597
2.
Complementarity of Hydrogen/Deuterium Exchange Mass Spectrometry and Cryo-Electron Microscopy.
Trends Biochem Sci
; 45(10): 906-918, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32487353
3.
The Light Chain Allosterically Enhances the Protease Activity of Murine Urokinase-Type Plasminogen Activator.
Biochemistry
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38780522
4.
The autoactivation of human single-chain urokinase-type plasminogen activator (uPA).
J Biol Chem
; 299(10): 105179, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607618
5.
Site-specific incorporation of biophysical probes into NF-ĸB with non-canonical amino acids.
Methods
; 213: 18-25, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36940840
6.
Allosteric couplings upon binding of RfaH to transcription elongation complexes.
Nucleic Acids Res
; 50(11): 6384-6397, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670666
7.
Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2.
Proc Natl Acad Sci U S A
; 118(23)2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088839
8.
Capturing the Dynamic Conformational Changes of Human Isocitrate Dehydrogenase 1 (IDH1) upon Ligand and Metal Binding Using Hydrogen-Deuterium Exchange Mass Spectrometry.
Biochemistry
; 62(6): 1145-1159, 2023 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854124
9.
An intrinsically disordered transcription activation domain increases the DNA binding affinity and reduces the specificity of NFκB p50/RelA.
J Biol Chem
; 298(9): 102349, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35934050
10.
The multifunctional role of intrinsic disorder in NF-κB signaling.
Biochem Soc Trans
; 51(6): 2085-2092, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38095058
11.
The Mechanism of NEDD8 Activation of CUL5 Ubiquitin E3 Ligases.
Mol Cell Proteomics
; 20: 100019, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268465
12.
Single-molecule conformational dynamics of a transcription factor reveals a continuum of binding modes controlling association and dissociation.
Nucleic Acids Res
; 49(19): 11211-11223, 2021 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34614173
13.
Dimer dissociation is a key energetic event in the fold-switch pathway of KaiB.
Biophys J
; 121(6): 943-955, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35151633
14.
How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen.
Biochemistry
; 61(2): 77-84, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34978431
15.
Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc Natl Acad Sci U S A
; 116(33): 16394-16403, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363053
16.
Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating.
Proc Natl Acad Sci U S A
; 116(28): 14309-14318, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31227607
17.
Hydrogen/Deuterium Exchange and Nuclear Magnetic Resonance Spectroscopy Reveal Dynamic Allostery on Multiple Time Scales in the Serine Protease Thrombin.
Biochemistry
; 60(46): 3441-3448, 2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34159782
18.
DECA, A Comprehensive, Automatic Post-processing Program for HDX-MS Data.
Mol Cell Proteomics
; 18(12): 2516-2523, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31594786
19.
Differential Local Stability Governs the Metamorphic Fold Switch of Bacterial Virulence Factor RfaH.
Biophys J
; 118(1): 96-104, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31810657
20.
Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2.
Nucleic Acids Res
; 46(1): 279-292, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29186573