Detalhe da pesquisa
1.
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures.
EMBO Rep
; 22(5): e51851, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932076
2.
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Nature
; 541(7635): 87-91, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002403
3.
Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem J
; 473(13): 1869-79, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27099339
4.
XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair.
Nat Cell Biol
; 23(12): 1287-1298, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34811483
5.
Impact of JNK and Its Substrates on Dendritic Spine Morphology.
Cells
; 9(2)2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32074971
6.
Deazaflavin Inhibitors of TDP2 with Cellular Activity Can Affect Etoposide Influx and/or Efflux.
ACS Chem Biol
; 14(6): 1110-1114, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31091068
7.
JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination.
Front Cell Neurosci
; 8: 272, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25309320
8.
c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells.
Mol Cell Biol
; 32(17): 3513-26, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22751924
9.
Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate.
Nat Neurosci
; 14(3): 305-13, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21297631