Detalhe da pesquisa
1.
The epichaperome is an integrated chaperome network that facilitates tumour survival.
Nature
; 538(7625): 397-401, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27706135
2.
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy.
Int J Mol Sci
; 22(3)2021 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33530349
3.
Human cyclophilin 40 unravels neurotoxic amyloids.
PLoS Biol
; 15(6): e2001336, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28654636
4.
The Right Tool for the Job: An Overview of Hsp90 Inhibitors.
Adv Exp Med Biol
; 1243: 135-146, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297216
5.
Hsp90 activator Aha1 drives production of pathological tau aggregates.
Proc Natl Acad Sci U S A
; 114(36): 9707-9712, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827321
6.
RNAi Screening of the Glucose-Regulated Chaperones in Cancer with Self-Assembled siRNA Nanostructures.
Nano Lett
; 16(10): 6099-6108, 2016 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27669096
7.
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism.
J Biol Chem
; 287(48): 40661-9, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035116
8.
Fixed Time-Point Analysis Reveals Repetitive Mild Traumatic Brain Injury Effects on Resting State Functional Magnetic Resonance Imaging Connectivity and Neuro-Spatial Protein Profiles.
J Neurotrauma
; 40(19-20): 2037-2049, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37051703
9.
The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.
J Biol Chem
; 286(19): 16976-83, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21367866
10.
Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice.
J Neurosci
; 30(29): 9651-8, 2010 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660248
11.
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.
J Neurosci
; 30(2): 591-9, 2010 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20071522
12.
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.
J Neurosci
; 30(46): 15374-82, 2010 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21084594
13.
Facilitating Akt clearance via manipulation of Hsp70 activity and levels.
J Biol Chem
; 285(4): 2498-505, 2010 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19889640
14.
Hsc70 rapidly engages tau after microtubule destabilization.
J Biol Chem
; 285(22): 16798-805, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20308058
15.
The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.
J Nat Prod
; 74(1): 38-44, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21141876
16.
Akt and CHIP coregulate tau degradation through coordinated interactions.
Proc Natl Acad Sci U S A
; 105(9): 3622-7, 2008 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18292230
17.
Effects of altered tau expression on dentate granule cell excitability in mice.
Exp Neurol
; 343: 113766, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34029610
18.
The Development of Hsp90ß-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition.
J Med Chem
; 64(3): 1545-1557, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33428418
19.
Chemical manipulation of hsp70 ATPase activity regulates tau stability.
J Neurosci
; 29(39): 12079-88, 2009 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19793966
20.
Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.
Am J Pathol
; 174(1): 228-38, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19074615