Detalhe da pesquisa
1.
A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker.
BMC Cancer
; 21(1): 510, 2021 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33957901
2.
Drug-free macromolecular therapeutics induce apoptosis in cells isolated from patients with B cell malignancies with enhanced apoptosis induction by pretreatment with gemcitabine.
Nanomedicine
; 16: 217-225, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639670
3.
Effect of a Pluronic(®) P123 formulation on the nitric oxide-generating drug JS-K.
Pharm Res
; 32(4): 1395-406, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25330743
4.
The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.
J Pharmacol Exp Ther
; 336(2): 313-20, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20962031
5.
Combination of the low anticoagulant heparin CX-01 with chemotherapy for the treatment of acute myeloid leukemia.
Blood Adv
; 2(4): 381-389, 2018 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467192
6.
An extensive pharmacokinetic, metabolic and toxicological review of elderly patients under intensive chemotherapy for acute myeloid leukemia.
Expert Opin Drug Metab Toxicol
; 11(1): 53-65, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488904
7.
Drug-free macromolecular therapeutics induce apoptosis of patient chronic lymphocytic leukemia cells.
Drug Deliv Transl Res
; 4(5-6): 389-94, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25580376
8.
Cellular distribution studies of the nitric oxide-generating antineoplastic prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate formulated in Pluronic P123 micelles.
J Pharm Pharmacol
; 65(9): 1329-36, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23927471
9.
JS-K, an arylating nitric oxide (NO) donor, has synergistic anti-leukemic activity with cytarabine (ARA-C).
Leuk Res
; 33(11): 1525-9, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19193435