Detalhe da pesquisa
1.
Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures.
Chem Res Toxicol
; 29(8): 1252-69, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404394
2.
The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure.
Int J Toxicol
; 33(6): 506-17, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25297719
3.
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.
Toxicol Mech Methods
; 24(7): 470-87, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25046638
4.
Digital pathology with artificial intelligence analysis provides insight to the efficacy of anti-fibrotic compounds in human 3D MASH model.
Sci Rep
; 14(1): 5885, 2024 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467661
5.
A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity.
Toxicol Appl Pharmacol
; 268(1): 1-16, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23352505
6.
ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation.
FASEB J
; 26(6): 2631-8, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22426118
7.
A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates.
Sci Rep
; 11(1): 22765, 2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815444
8.
Tumor necrosis factor alpha and phorbol 12-myristate-13-acetate down-regulate human 11beta-hydroxysteroid dehydrogenase type 2 through p50/p50 NF-kappaB homodimers and Egr-1.
FASEB J
; 19(6): 650-2, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15659537
9.
PPARs in diseases: control mechanisms of inflammation.
Curr Med Chem
; 12(25): 2995-3009, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16378501
10.
Hypoxia causes down-regulation of 11 beta-hydroxysteroid dehydrogenase type 2 by induction of Egr-1.
FASEB J
; 17(8): 917-9, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12626438
11.
Impact assessment of repeated exposure of organotypic 3D bronchial and nasal tissue culture models to whole cigarette smoke.
J Vis Exp
; (96)2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25741927
12.
Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues.
Biomed Res Int
; 2013: 512086, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24224167
13.
Poly(ADP-ribose)polymerase-1 (PARP1) controls adipogenic gene expression and adipocyte function.
Mol Endocrinol
; 26(1): 79-86, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22053002
14.
GW501516-activated PPARß/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation.
Cell Biosci
; 2(1): 34, 2012 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23046570
15.
Tumor necrosis factor-alpha upregulates 11beta-hydroxysteroid dehydrogenase type 1 expression by CCAAT/enhancer binding protein-beta in HepG2 cells.
Am J Physiol Endocrinol Metab
; 296(2): E367-77, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19088256
16.
Dehydroepiandrosterone inhibits the amplification of glucocorticoid action in adipose tissue.
Am J Physiol Endocrinol Metab
; 288(5): E957-64, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15613680
17.
In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3.
J Biol Chem
; 277(17): 14647-56, 2002 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-11850421