Detalhe da pesquisa
1.
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses.
Immunity
; 39(4): 758-69, 2013 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035365
2.
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation.
J Immunol
; 188(8): 3734-44, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22427637
3.
Translatability of findings from cynomolgus monkey to human suggests a mechanistic role for IL-21 in promoting immunogenicity to an anti-PD-1/IL-21 mutein fusion protein.
Front Immunol
; 15: 1345473, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343535
4.
Survey Outcome on Immunogenicity Risk Assessment Tools for Biotherapeutics: an Insight into Consensus on Methods, Application, and Utility in Drug Development.
AAPS J
; 25(4): 55, 2023 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37266912
5.
Immunogenicity assessment of bispecific antibody-based immunotherapy in oncology.
J Immunother Cancer
; 10(4)2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35444060
6.
Assay format diversity in pre-clinical immunogenicity risk assessment: Toward a possible harmonization of antigenicity assays.
MAbs
; 14(1): 1993522, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923896
7.
EAE mediated by a non-IFN-γ/non-IL-17 pathway.
Eur J Immunol
; 40(8): 2340-8, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20540117
8.
IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway.
Brain Behav Immun
; 25(5): 932-7, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20951792
9.
Immunogenicity Risk Assessment for Multi-specific Therapeutics.
AAPS J
; 23(6): 115, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34741215
10.
Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target.
Front Immunol
; 12: 782788, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34970265
11.
Clinical immunogenicity of the d-amino acid peptide therapeutic etelcalcetide: Method development challenges and anti-drug antibody clinical impact assessments.
J Immunol Methods
; 445: 37-44, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274835
12.
Assay signal as an alternative to titer for assessment of magnitude of an antidrug antibody response.
Bioanalysis
; 9(23): 1849-1858, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29020795
13.
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms.
J Exp Med
; 212(4): 539-53, 2015 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25824819
14.
Development and optimization of neutralizing antibody assays to monitor clinical immunogenicity.
Bioanalysis
; 4(22): 2725-35, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23210655
15.
GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.
J Exp Med
; 207(5): 953-61, 2010 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20421390
16.
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.
J Exp Med
; 205(7): 1535-41, 2008 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18573909
17.
Th17 and Th1 responses directed against the immunizing epitope, as opposed to secondary epitopes, dominate the autoimmune repertoire during relapses of experimental autoimmune encephalomyelitis.
J Neurosci Res
; 85(8): 1685-93, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17465017