Detalhe da pesquisa
1.
Discovery of BI 135585, an in vivo efficacious oxazinanone-based 11ß hydroxysteroid dehydrogenase type 1 inhibitor.
Bioorg Med Chem
; 25(14): 3649-3657, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28528082
2.
Discovery and optimization of adamantyl carbamate inhibitors of 11ß-HSD1.
Bioorg Med Chem Lett
; 20(22): 6725-9, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20864344
3.
Spirocyclic ureas: orally bioavailable 11 beta-HSD1 inhibitors identified by computer-aided drug design.
Bioorg Med Chem Lett
; 20(3): 881-6, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064717
4.
Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11ß-hydroxysteroid dehydrogenase type 1.
J Med Chem
; 54(17): 6050-62, 2011 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21786805
5.
Immunohistochemical discrimination between the ASPL-TFE3 fusion proteins of alveolar soft part sarcoma.
J Pediatr Hematol Oncol
; 30(1): 46-52, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18176180
6.
Relationship between autophosphorylation and phosphorylation of exogenous substrates by the human cytomegalovirus UL97 protein kinase.
J Virol
; 76(23): 11943-52, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12414936
7.
The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress.
J Virol
; 77(2): 905-14, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12502806
8.
Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase. Importance of the P+5 position.
J Biol Chem
; 277(33): 29593-9, 2002 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12048183
9.
Phosphorylation of the RNA polymerase II carboxyl-terminal domain in human cytomegalovirus-infected cells and in vitro by the viral UL97 protein kinase.
Virology
; 324(1): 184-93, 2004 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15183065
10.
The human cytomegalovirus UL44 protein is a substrate for the UL97 protein kinase.
J Virol
; 77(14): 7720-7, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12829811
11.
Phosphorylation of beta-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirus.
Antimicrob Agents Chemother
; 46(2): 478-86, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11796361