1.
Bull Exp Biol Med
; 175(1): 112-115, 2023 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37336808
RESUMO
In female Wistar rats, mammary gland hyperplasia (MGH) was modeled according to a modified protocol involving estrogen-progesterone induction and taking into account the duration of the estrous cycle of this animal species. MGH was induced over four 7-day cycles; each cycle included subcutaneous administration of 17ß-estradiol (0.5 mg/kg) for 4 days, injection of progesterone (5 mg/kg) on day 5, then 2 days without injections. In females with MGH, a significant increase in the height and diameter of the nipples of the mammary glands was recorded, two types of changes were observed in the gland tissue: tubuloalveolar and lobuloalveolar hyperplasia. The study confirmed the development of MGH in rats by a modified method.
Assuntos
Estrogênios , Progesterona , Ratos , Feminino , Animais , Progesterona/farmacologia , Hiperplasia/induzido quimicamente , Hiperplasia/patologia , Ratos Wistar , Estrogênios/farmacologia , Estradiol/farmacologia , Glândulas Mamárias Animais/patologia
2.
Voen Med Zh
; (9): 26-7, 1975 Sep.
Artigo
em Russo
| MEDLINE
| ID: mdl-1181715
3.
Gig Sanit
; (9): 104-6, 1976 Sep.
Artigo
em Russo
| MEDLINE
| ID: mdl-1017636
4.
Med Radiol (Mosk)
; 19(10): 33-8, 1974 Oct.
Artigo
em Russo
| MEDLINE
| ID: mdl-4431294