Detalhe da pesquisa
1.
Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression.
Eur Respir J
; 60(2)2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35086832
2.
Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping.
Am J Hum Genet
; 101(3): 326-339, 2017 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28844486
3.
Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function.
Eur Respir J
; 52(3)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30166324
4.
Optimal correction of distinct CFTR folding mutants in rectal cystic fibrosis organoids.
Eur Respir J
; 48(2): 451-8, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27103391
5.
ß2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.
Eur Respir J
; 48(3): 768-79, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27471203
6.
Comparison of Organoid Swelling and In Vivo Biomarkers of CFTR Function to Determine Effects of Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for the F508del Mutation.
Am J Respir Crit Care Med
; 202(11): 1589-1592, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32687398
7.
High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing.
ERJ Open Res
; 9(1)2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36726369
8.
Exploring intrinsic variability between cultured nasal and bronchial epithelia in cystic fibrosis.
Sci Rep
; 13(1): 18573, 2023 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37903789
9.
Isolation of deletion alleles by G4 DNA-induced mutagenesis.
Nat Methods
; 6(9): 655-7, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19684597
10.
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia.
Life Sci Alliance
; 5(12)2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35922154
11.
Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans.
Curr Biol
; 18(12): 900-5, 2008 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18538569
12.
R117H-CFTR function and response to VX-770 correlate with mRNA and protein expression in intestinal organoids.
J Cyst Fibros
; 19(5): 728-732, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32061518
13.
Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids.
STAR Protoc
; 1(1): 100019, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33111074
14.
Clinical effects of the three CFTR potentiator treatments curcumin, genistein and ivacaftor in patients with the CFTR-S1251N gating mutation.
J Cyst Fibros
; 19(6): 955-961, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32499204
15.
Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations.
J Cyst Fibros
; 19(4): 614-619, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31735562
16.
CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank.
Cell Stem Cell
; 26(4): 503-510.e7, 2020 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32084388
17.
Folding-function relationship of the most common cystic fibrosis-causing CFTR conductance mutants.
Life Sci Alliance
; 2(1)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30659068
18.
Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.
Cell Rep
; 26(7): 1701-1708.e3, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30759382
19.
Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity.
J Cyst Fibros
; 17(3): 316-324, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29544685
20.
Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells.
Genome Med
; 9(1): 9, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28126037