Detalhe da pesquisa
1.
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Cell
; 160(4): 745-758, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25662011
2.
Variation in histone configurations correlates with gene expression across nine inbred strains of mice.
Genome Res
; 33(6): 857-871, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37217254
3.
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.
Am J Hum Genet
; 102(4): 620-635, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29625024
4.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
; 27(2): 208-222, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864352
5.
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes.
Proc Natl Acad Sci U S A
; 114(9): 2301-2306, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193859
6.
Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation.
Gastroenterology
; 152(7): 1638-1646, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28192105
7.
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.
J Immunol
; 196(1): 437-47, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26582949
8.
Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function.
Curr Diab Rep
; 15(9): 66, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272056
9.
Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats.
Hepatology
; 57(5): 1763-72, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23175050
10.
Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents.
Hepatology
; 55(3): 781-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22105854
11.
Alterations in adipose tissue distribution, cell morphology and function mark primary insulin hypersecretion in youths with obesity.
Diabetes
; 2023 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37870826
12.
A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents.
Hepatology
; 52(4): 1281-90, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20803499
13.
Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive ß cell transcriptional activation.
Nat Commun
; 12(1): 5242, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475398
14.
Tet2 Controls the Responses of ß cells to Inflammation in Autoimmune Diabetes.
Nat Commun
; 12(1): 5074, 2021 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417463
15.
AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data.
Genome Biol
; 22(1): 252, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34465366
16.
Glucose dysregulation and hepatic steatosis in obese adolescents: is there a link?
Hepatology
; 49(6): 1896-903, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19434725
17.
Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls.
Diabetes
; 68(6): 1168-1177, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936147
18.
Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic ß Cell Identity and Function.
Cell Rep
; 26(3): 788-801.e6, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30650367
19.
Modulation of TSHR signaling by posttranslational modifications.
Trends Endocrinol Metab
; 18(5): 199-207, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17524661
20.
The "adipose tissue expandability" hypothesis: a potential mechanism for insulin resistance in obese youth.
Horm Mol Biol Clin Investig
; 33(2)2018 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29596053