Detalhe da pesquisa
1.
Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators.
Bioorg Chem
; 108: 104614, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508678
2.
Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.
Bioorg Med Chem
; 23(24): 7717-27, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631441
3.
Amelioration of Astrocyte-Mediated Neuroinflammation by EI-16004 Confers Neuroprotection in an MPTP-induced Parkinson's Disease Model.
Neuromolecular Med
; 26(1): 1, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294608
4.
Physicochemical characterization and phase II metabolic profiling of echinochrome A, a bioactive constituent from sea urchin, and its physiologically based pharmacokinetic modeling in rats and humans.
Biomed Pharmacother
; 162: 114589, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37004327
5.
A bioisosteric approach to the discovery of novel N-aryl-N'-[4-(aryloxy)cyclohexyl]squaramide-based activators of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation.
Eur J Med Chem
; 239: 114501, 2022 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716517
6.
Discovery and optimization of novel 3-benzyl-N-phenyl-1H-pyrazole-5-carboxamides as bifunctional antidiabetic agents stimulating both insulin secretion and glucose uptake.
Eur J Med Chem
; 217: 113325, 2021 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33765605
7.
Pharmacokinetic Evaluation of Metabolic Drug Interactions between Repaglinide and Celecoxib by a Bioanalytical HPLC Method for Their Simultaneous Determination with Fluorescence Detection.
Pharmaceutics
; 11(8)2019 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31382371
8.
Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain.
Eur J Med Chem
; 97: 245-58, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25984841