Detalhe da pesquisa
1.
KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
Cell
; 161(2): 333-47, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25860612
2.
The N-end rule pathway.
Annu Rev Biochem
; 81: 261-89, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22524314
3.
The N-Degron Pathway Mediates ER-phagy.
Mol Cell
; 75(5): 1058-1072.e9, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31375263
4.
UBR2 targets myosin heavy chain IIb and IIx for degradation: Molecular mechanism essential for cancer-induced muscle wasting.
Proc Natl Acad Sci U S A
; 119(43): e2200215119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36252004
5.
UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism.
Am J Hum Genet
; 108(1): 134-147, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340455
6.
The N-terminal cysteine is a dual sensor of oxygen and oxidative stress.
Proc Natl Acad Sci U S A
; 118(50)2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34893540
7.
Phosphorylation of ß-catenin Ser60 by polo-like kinase 1 drives the completion of cytokinesis.
EMBO Rep
; 22(12): e51503, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34585824
8.
The N-end rule pathway: emerging functions and molecular principles of substrate recognition.
Nat Rev Mol Cell Biol
; 12(11): 735-47, 2011 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22016057
9.
Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms.
Proc Natl Acad Sci U S A
; 117(47): 29823-29831, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168738
10.
Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
Proc Natl Acad Sci U S A
; 117(31): 18661-18669, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32675242
11.
Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.
Proc Natl Acad Sci U S A
; 117(32): 19190-19200, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723828
12.
Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles.
Proc Natl Acad Sci U S A
; 116(16): 7805-7812, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867293
13.
The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy.
Trends Biochem Sci
; 42(11): 873-886, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947091
14.
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Proc Natl Acad Sci U S A
; 115(12): E2716-E2724, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29507222
15.
The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome.
J Cell Sci
; 131(17)2018 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30111582
16.
CPPF, A Novel Microtubule Targeting Anticancer Agent, Inhibits the Growth of a Wide Variety of Cancers.
Int J Mol Sci
; 21(13)2020 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645923
17.
Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.
J Biol Chem
; 293(3): 847-862, 2018 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29191835
18.
Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition.
EMBO Rep
; 18(1): 150-168, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27993939
19.
Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal.
Bioessays
; 39(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28493408
20.
p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome.
Proc Natl Acad Sci U S A
; 113(47): E7490-E7499, 2016 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791183