Detalhe da pesquisa
1.
N-Phenylpyridine-3-Carboxamide and 6-Acetyl-1H-Indazole Inhibit the RNA Replication Step of the Dengue Virus Life Cycle.
Antimicrob Agents Chemother
; 67(2): e0133122, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36700643
2.
Drug Self-Aggregation into Nano-Entities Has the Potential to Induce Immune Responses.
Mol Pharm
; 20(8): 4031-4040, 2023 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37421372
3.
Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.
Bioorg Med Chem Lett
; 95: 129488, 2023 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770003
4.
Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?
Arch Toxicol
; 96(9): 2559-2572, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666269
5.
Synthesis of NSC 106084 and NSC 14778 and evaluation of their DNMT inhibitory activity.
Bioorg Med Chem Lett
; 29(6): 826-831, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30704813
6.
NMR strategies to support medicinal chemistry workflows for primary structure determination.
Bioorg Med Chem Lett
; 27(2): 242-247, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913183
7.
The Search for Antidotes Against Ricin.
Mini Rev Med Chem
; 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38350844
8.
NMR spectroscopy can help accelerate antiviral drug discovery programs.
Microbes Infect
; : 105297, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199267
9.
Molecular Dynamics of Outer Membrane-Embedded Polysaccharide Secretion Porins Reveals Closed Resting-State Surface Gates Targetable by Virtual Fragment Screening for Drug Hotspot Identification.
ACS Omega
; 9(11): 13217-13226, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38524450
10.
Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy.
Nat Commun
; 15(1): 4175, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38755132
11.
N- versus O-alkylation: utilizing NMR methods to establish reliable primary structure determinations for drug discovery.
Bioorg Med Chem Lett
; 23(16): 4663-8, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23809849
12.
Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors.
Bioorg Med Chem Lett
; 23(9): 2775-80, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23511023
13.
Determining the Predominant Conformations of Mortiamides A-D in Solution Using NMR Data and Molecular Modeling Tools.
ACS Omega
; 8(29): 25832-25838, 2023 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37521620
14.
Molecular modeling of Mannich phenols as reactivators of human acetylcholinesterase inhibited by A-series nerve agents.
Chem Biol Interact
; 382: 110622, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442286
15.
Computational design of candidate multi-epitope vaccine against SARS-CoV-2 targeting structural (S and N) and non-structural (NSP3 and NSP12) proteins.
J Biomol Struct Dyn
; 41(22): 13348-13367, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36744449
16.
Molecular modeling study of natural products as potential bioactive compounds against SARS-CoV-2.
J Mol Model
; 29(6): 183, 2023 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37212923
17.
A Multi-epitope Vaccine Candidate Against Bolivian Hemorrhagic fever Caused by Machupo Virus.
Appl Biochem Biotechnol
; 2023 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37479961
18.
Robust Strategy for Hit-to-Lead Discovery: NMR for SAR.
J Med Chem
; 66(19): 13416-13427, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37732695
19.
Practical Considerations and Guidelines for Spectral Referencing for Fluorine NMR Ligand Screening.
ACS Omega
; 7(15): 13155-13163, 2022 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35474811
20.
Modeling studies on the role of vitamins B1 (thiamin), B3 (nicotinamide), B6 (pyridoxamine), and caffeine as potential leads for the drug design against COVID-19.
J Mol Model
; 28(12): 380, 2022 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36342543