Detalhe da pesquisa
1.
Quantitation of amyloid beta peptides Aß(1-38), Aß(1-40), and Aß(1-42) in human cerebrospinal fluid by ultra-performance liquid chromatography-tandem mass spectrometry.
Anal Biochem
; 419(2): 133-9, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21888888
2.
Discovery of N-benzyl-2-[(4S)-4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]-N-isopropylacetamide, an orally active, gut-selective CCK1 receptor agonist for the potential treatment of obesity.
Bioorg Med Chem Lett
; 20(22): 6797-801, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20851601
3.
Development of an UPLC/MS-MS method for quantification of intact IGF-I from human serum.
Bioanalysis
; 12(1): 53-65, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31849266
4.
Modification of amyloid-beta(1-40) by a protease inhibitor creates risk of error in mass spectrometric quantitation of amyloid-beta(1-42).
Anal Biochem
; 382(2): 147-9, 2008 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18706385
5.
Application of a linear ion trap/orbitrap mass spectrometer in metabolite characterization studies: examination of the human liver microsomal metabolism of the non-tricyclic anti-depressant nefazodone using data-dependent accurate mass measurements.
J Am Soc Mass Spectrom
; 17(3): 363-75, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16442304
6.
Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4.
Chem Biol Interact
; 155(1-2): 10-20, 2005 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-15978881
7.
Practical applications of integrated microfluidics for peptide quantification.
Bioanalysis
; 7(7): 857-67, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25932520
8.
Intravenous pharmacokinetics and metabolism of the reactive oxygen scavenger alpha-phenyl-N-tert-butyl nitrone (PBN) in the cynomolgus monkey.
Drug Metabol Drug Interact
; 20(1-2): 11-24, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15283300
9.
High sensitivity LC-MS/MS method for direct quantification of human parathyroid 1-34 (teriparatide) in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci
; 938: 96-104, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076523
10.
Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation.
Drug Metab Dispos
; 35(6): 848-58, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17344339
11.
Bioactivation of the nontricyclic antidepressant nefazodone to a reactive quinone-imine species in human liver microsomes and recombinant cytochrome P450 3A4.
Drug Metab Dispos
; 33(2): 243-53, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15523046
12.
Pharmacokinetics and metabolism of the reactive oxygen scavenger alpha-phenyl-N-tert-butylnitrone in the male Sprague-Dawley rat.
Drug Metab Dispos
; 31(2): 147-52, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12527695
13.
Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1.
Bioorg Med Chem Lett
; 14(13): 3389-95, 2004 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15177439