Detalhe da pesquisa
1.
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Cell
; 159(7): 1549-62, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25525874
2.
Termination of STING responses is mediated via ESCRT-dependent degradation.
EMBO J
; 42(12): e112712, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37139896
3.
Physiological restraint of Bak by Bcl-xL is essential for cell survival.
Genes Dev
; 30(10): 1240-50, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27198225
4.
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis.
Nat Chem Biol
; 15(11): 1057-1066, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591564
5.
Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion.
Blood
; 132(2): 197-209, 2018 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29784641
6.
Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival.
Blood
; 119(24): 5850-8, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22374700
7.
Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells.
Cell Rep
; 36(3): 109430, 2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34289356
8.
Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice.
Blood Adv
; 4(7): 1270-1283, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32236527
9.
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Science
; 359(6378)2018 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472455
10.
Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.
J Clin Invest
; 127(3): 814-829, 2017 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28134622
11.
IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.
Cell Metab
; 23(1): 155-64, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603191
12.
Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.
Nat Commun
; 5: 3455, 2014 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24632563
13.
ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.
Cell Metab
; 18(2): 225-38, 2013 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23931754
14.
Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.
J Exp Med
; 208(10): 2017-31, 2011 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21911424