Detalhe da pesquisa
1.
A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy.
J Neuroinflammation
; 17(1): 223, 2020 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32711525
2.
The Amyloid-Tau-Neuroinflammation Axis in the Context of Cerebral Amyloid Angiopathy.
Int J Mol Sci
; 20(24)2019 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31847365
3.
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.
J Neurosci
; 34(12): 4260-72, 2014 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24647946
4.
Amyloid-ß oligomers as a template for secondary amyloidosis in Alzheimer's disease.
Neurobiol Dis
; 71: 14-23, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25134727
5.
Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity.
Biochem Biophys Res Commun
; 430(3): 963-8, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23261448
6.
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease.
FASEB J
; 26(5): 1946-59, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22253473
7.
TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo.
Cells
; 12(12)2023 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37371067
8.
Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer's disease.
bioRxiv
; 2023 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37546928
9.
Therapeutic targeting of immunometabolism in Alzheimer's disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression.
bioRxiv
; 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014106
10.
Network analysis reveals strain-dependent response to misfolded tau aggregates.
bioRxiv
; 2023 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36778440
11.
TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation.
Genome Med
; 15(1): 11, 2023 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36805764
12.
Network analysis identifies strain-dependent response to tau and tau seeding-associated genes.
J Exp Med
; 220(11)2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37606887
13.
Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation.
ACS Chem Neurosci
; 14(21): 3913-3927, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37818657
14.
Amyloid-ß annular protofibrils evade fibrillar fate in Alzheimer disease brain.
J Biol Chem
; 286(25): 22122-30, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21507938
15.
The reduction of astrocytic tau prevents amyloid-ß-induced synaptotoxicity.
Brain Commun
; 4(5): fcac235, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36196088
16.
Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy.
Neurobiol Aging
; 109: 52-63, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34655981
17.
Activated endothelial cells induce a distinct type of astrocytic reactivity.
Commun Biol
; 5(1): 282, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35351973
18.
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.
Sci Transl Med
; 14(637): eabl7634, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320002
19.
CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
Mol Neurodegener
; 17(1): 47, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764973
20.
Bassoon contributes to tau-seed propagation and neurotoxicity.
Nat Neurosci
; 25(12): 1597-1607, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36344699