Detalhe da pesquisa
1.
Complementary yet divergent effects of exercise and an exercise mimetic on microbiome in high-fat diet-induced obesity.
Physiol Genomics
; 56(2): 136-144, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38009223
2.
Tau suppresses microtubule-regulated pancreatic insulin secretion.
Mol Psychiatry
; 28(9): 3982-3993, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37735502
3.
XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.
Diabetologia
; 65(6): 984-996, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35316840
4.
Transcriptome analysis of islets from diabetes-resistant and diabetes-prone obese mice reveals novel gene regulatory networks involved in beta-cell compensation and failure.
FASEB J
; 35(6): e21608, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33977593
5.
Concurrent betaine administration enhances exercise-induced improvements to glucose handling in obese mice.
Nutr Metab Cardiovasc Dis
; 32(10): 2439-2449, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36096978
6.
A fluorescent timer reporter enables sorting of insulin secretory granules by age.
J Biol Chem
; 295(27): 8901-8911, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32341128
7.
Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes.
Diabetologia
; 62(6): 993-999, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830262
8.
Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
Diabetologia
; 62(12): 2273-2286, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31624901
9.
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to ß-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
PLoS Genet
; 12(5): e1006033, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27195491
10.
Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes.
J Biol Chem
; 291(49): 25629-25640, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738101
11.
Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.
Diabetologia
; 59(7): 1492-1502, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27039902
12.
Chronic high-fat diet in fathers programs ß-cell dysfunction in female rat offspring.
Nature
; 467(7318): 963-6, 2010 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20962845
13.
Inhibitor of differentiation proteins protect against oxidative stress by regulating the antioxidant-mitochondrial response in mouse beta cells.
Diabetologia
; 58(4): 758-70, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25636209
14.
Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes.
Diabetologia
; 56(10): 2203-12, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23842730
15.
Inhibition of PKCepsilon improves glucose-stimulated insulin secretion and reduces insulin clearance.
Cell Metab
; 6(4): 320-8, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17908560
16.
A lipidomic screen of palmitate-treated MIN6 ß-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking.
Biochem J
; 435(1): 267-76, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21265737
17.
Iron chelation increases beige fat differentiation and metabolic activity, preventing and treating obesity.
Sci Rep
; 12(1): 776, 2022 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031684
18.
Neuropeptide Y1 receptor antagonism protects ß-cells and improves glycemic control in type 2 diabetes.
Mol Metab
; 55: 101413, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890851
19.
Emerging Roles of Metallothioneins in Beta Cell Pathophysiology: Beyond and Above Metal Homeostasis and Antioxidant Response.
Biology (Basel)
; 10(3)2021 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33652748
20.
The Role of Fatty Acid Signaling in Islet Beta-Cell Adaptation to Normal Pregnancy.
Front Endocrinol (Lausanne)
; 12: 799081, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35069446