Detalhe da pesquisa
1.
The role of alanine glyoxylate transaminase-2 (agxt2) in ß-alanine and carnosine metabolism of healthy mice and humans.
Eur J Appl Physiol
; 120(12): 2749-2759, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32948897
2.
Rapid onset of severe septic shock in the pregnant mouse.
Biol Reprod
; 100(2): 505-513, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30184059
3.
Regulation of fluid reabsorption in rat or mouse proximal renal tubules by asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase 1.
Am J Physiol Renal Physiol
; 315(1): F74-F78, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513072
4.
NRF2 prevents hypertension, increased ADMA, microvascular oxidative stress, and dysfunction in mice with two weeks of ANG II infusion.
Am J Physiol Regul Integr Comp Physiol
; 314(3): R399-R406, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29167164
5.
Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity.
Crit Care
; 22(1): 336, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30538005
6.
The response of the innate immune and cardiovascular systems to LPS in pregnant and nonpregnant mice.
Biol Reprod
; 97(2): 258-272, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29044422
7.
Endothelial Dimethylarginine Dimethylaminohydrolase 1 Is an Important Regulator of Angiogenesis but Does Not Regulate Vascular Reactivity or Hemodynamic Homeostasis.
Circulation
; 131(25): 2217-25, 2015 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25910799
8.
Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs.
Circulation
; 131(7): 633-42, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25492024
9.
Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis.
Exp Eye Res
; 147: 148-155, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27181226
10.
Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in polymicrobial sepsis.
Arterioscler Thromb Vasc Biol
; 35(6): 1382-92, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25857313
11.
Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.
J Am Soc Nephrol
; 26(12): 3045-59, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25855779
12.
Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study.
Lancet
; 384(9942): 504-13, 2014 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24794816
13.
Pharmacological inhibition of DDAH1 improves survival, haemodynamics and organ function in experimental septic shock.
Biochem J
; 460(2): 309-16, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24611830
14.
miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.
Biochem J
; 462(1): 103-12, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895913
15.
Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.
Circulation
; 128(8): 845-53, 2013 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23825361
16.
Disruption of methylarginine metabolism impairs vascular homeostasis.
Nat Med
; 13(2): 198-203, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17273169
17.
Asymmetric Dimethylarginine Enables Depolarizing Spikes and Vasospasm in Mesenteric and Coronary Resistance Arteries.
Hypertension
; 81(4): 764-775, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38226470
18.
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?
Arterioscler Thromb Vasc Biol
; 32(6): 1343-53, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22460557
19.
Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure.
Arterioscler Thromb Vasc Biol
; 32(12): 2892-900, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23023372
20.
Genetic and pharmacological inhibition of dimethylarginine dimethylaminohydrolase 1 is protective in endotoxic shock.
Arterioscler Thromb Vasc Biol
; 32(11): 2589-97, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22995517