Detalhe da pesquisa
1.
Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
FASEB J
; 33(1): 557-571, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30001166
2.
Glioma: experimental models and reality.
Acta Neuropathol
; 133(2): 263-282, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28074274
3.
Imaging Hyperpolarized Pyruvate and Lactate after Blood-Brain Barrier Disruption with Focused Ultrasound.
ACS Chem Neurosci
; 10(5): 2591-2601, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30873831
4.
Mapping actionable pathways and mutations in brain tumours using targeted RNA next generation sequencing.
Acta Neuropathol Commun
; 7(1): 185, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31747973
5.
Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate.
Cancer Metab
; 7: 4, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31139406
6.
In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma.
Oncotarget
; 8(30): 49165-49177, 2017 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467784
7.
Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.
Sci Rep
; 6: 30486, 2016 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27460417
8.
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
Cancer Res
; 75(22): 4790-802, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26363012