Detalhe da pesquisa
1.
Single-stranded siRNAs activate RNAi in animals.
Cell
; 150(5): 883-94, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22939618
2.
Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans.
PLoS Biol
; 19(11): e3001431, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34723964
3.
A phase Ib trial of mivavotinib (TAK-659), a dual SYK/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia.
Haematologica
; 108(3): 705-716, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36226495
4.
Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning.
Am J Physiol Endocrinol Metab
; 321(3): E433-E442, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34370596
5.
Randomised trial and open-label extension study of an anti-interleukin-6 antibody in Crohn's disease (ANDANTE I and II).
Gut
; 68(1): 40-48, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29247068
6.
Quantitative Translational Analysis of Brain Kynurenic Acid Modulation via Irreversible Kynurenine Aminotransferase II Inhibition.
Mol Pharmacol
; 94(2): 823-833, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29853495
7.
Pharmacokinetics and C-reactive protein modelling of anti-interleukin-6 antibody (PF-04236921) in healthy volunteers and patients with autoimmune disease.
Br J Clin Pharmacol
; 84(9): 2059-2074, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29776017
8.
Efficacy and safety of an interleukin 6 monoclonal antibody for the treatment of systemic lupus erythematosus: a phase II dose-ranging randomised controlled trial.
Ann Rheum Dis
; 76(3): 534-542, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27672124
9.
A sustained dietary change increases epigenetic variation in isogenic mice.
PLoS Genet
; 7(4): e1001380, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21541011
10.
A phase Ib study evaluating the recommended phase II dose, safety, tolerability, and efficacy of mivavotinib in combination with nivolumab in advanced solid tumors.
Cancer Med
; 13(5)2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38501219
11.
Expanding the spectrum of IDH1 mutations in gliomas.
Mod Pathol
; 26(5): 619-25, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23307057
12.
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells.
RNA Biol
; 10(8): 1333-44, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23807490
13.
Population Pharmacokinetics of Mivavotinib (TAK-659), a Dual Spleen Tyrosine Kinase and FMS-Like Tyrosine Kinase 3 Inhibitor, in Patients With Advanced Solid Tumors or Hematologic Malignancies.
J Clin Pharmacol
; 63(3): 326-337, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36309821
14.
Pharmacokinetic-pharmacodynamic modeling of the D2 and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats.
Pharm Res
; 29(7): 1932-48, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22437487
15.
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the dopamine D2 receptor occupancy of olanzapine in rats.
Pharm Res
; 28(10): 2490-504, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21647790
16.
The stability of chicken nucleoside triphosphate diphosphohydrolase 8 requires both of its transmembrane domains.
Biochemistry
; 49(1): 134-46, 2010 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20000380
17.
Oligoastrocytomas: throwing the baby out with the bathwater?
Acta Neuropathol
; 129(1): 147-9, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25304041
18.
Population pharmacokinetic modeling of PF-06439535 (a bevacizumab biosimilar) and reference bevacizumab (Avastin®) in patients with advanced non-squamous non-small cell lung cancer.
Cancer Chemother Pharmacol
; 85(3): 487-499, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768697
19.
Molecular epidemiology of hepatitis C genotype 6a from patients with chronic hepatitis C from Hong Kong.
J Med Virol
; 81(4): 628-33, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19235848
20.
Prevalence of diarrhea viruses in hospitalized children in Hong Kong in 2008.
J Med Virol
; 81(11): 1903-11, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19774686