Detalhe da pesquisa
1.
Integration of metabolomics and proteomics reveals the underlying hepatotoxic mechanism of perfluorooctane sulfonate (PFOS) and 6:2 chlorinated polyfluoroalkyl ether sulfonic acid (6:2 Cl-PFESA) in primary human hepatocytes.
Ecotoxicol Environ Saf
; 249: 114361, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36508832
2.
Binding and activity of bisphenol analogues to human peroxisome proliferator-activated receptor ß/δ.
Ecotoxicol Environ Saf
; 226: 112849, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34627044
3.
Lipid metabolism disorders effects of 6:2 chlorinated polyfluorinated ether sulfonate through Hsa-miRNA-532-3p/Acyl-CoA oxidase 1(ACOX1) pathway.
Ecotoxicol Environ Saf
; 228: 113011, 2021 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837870
4.
MicroRNA hsa-miR-1301-3p Regulates Human ADH6, ALDH5A1 and ALDH8A1 in the Ethanol-Acetaldehyde-Acetate Metabolic Pathway.
Mol Pharmacol
; 98(2): 120-129, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32499331
5.
Receptor-Bound Perfluoroalkyl Carboxylic Acids Dictate Their Activity on Human and Mouse Peroxisome Proliferator-Activated Receptor γ.
Environ Sci Technol
; 54(15): 9529-9536, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32639727
6.
Perfluoroalkyl Substances Stimulate Insulin Secretion by Islet ß Cells via G Protein-Coupled Receptor 40.
Environ Sci Technol
; 54(6): 3428-3436, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092270
7.
Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity.
Ecotoxicol Environ Saf
; 205: 111166, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32827966
8.
Adipogenic Activity of Oligomeric Hexafluoropropylene Oxide (Perfluorooctanoic Acid Alternative) through Peroxisome Proliferator-Activated Receptor γ Pathway.
Environ Sci Technol
; 53(6): 3287-3295, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30785727
9.
Binding and activity of sulfated metabolites of lower-chlorinated polychlorinated biphenyls towards thyroid hormone receptor alpha.
Ecotoxicol Environ Saf
; 180: 686-692, 2019 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31146155
10.
Chlorinated Polyfluoroalkylether Sulfonates Exhibit Similar Binding Potency and Activity to Thyroid Hormone Transport Proteins and Nuclear Receptors as Perfluorooctanesulfonate.
Environ Sci Technol
; 52(16): 9412-9418, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30052437
11.
Chlorinated Polyfluorinated Ether Sulfonates Exhibit Higher Activity toward Peroxisome Proliferator-Activated Receptors Signaling Pathways than Perfluorooctanesulfonate.
Environ Sci Technol
; 52(5): 3232-3239, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29389105
12.
Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway.
Environ Sci Technol
; 51(19): 11423-11430, 2017 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28858478
13.
Competitive relationships due to similar nutrient preferences reshape soil bacterial metacommunities.
Sci Total Environ
; 933: 172956, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38719036
14.
Triclocarban exhibits higher adipogenic activity than triclosan through peroxisome proliferator-activated receptors pathways.
Environ Pollut
; 342: 123030, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38030110
15.
Binding, activity and risk assessment of bisphenols toward farnesoid X receptor pathway: In vitro and in silico study.
Sci Total Environ
; 869: 161701, 2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36709907
16.
Human health risk assessment of 6:2 Cl-PFESA through quantitative in vitro to in vivo extrapolation by integrating cell-based assays, an epigenetic key event, and physiologically based pharmacokinetic modeling.
Environ Int
; 173: 107846, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36842380
17.
Toxicity and risk priority ranking of polybrominated diphenyl ethers (PBDEs): A relative receptor-bound concentration approach.
Sci Total Environ
; 892: 164714, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37302604
18.
Lysine ß-hydroxybutyrylation promotes lipid accumulation in alcoholic liver disease.
Biochem Pharmacol
; : 115936, 2023 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38012969
19.
Using a human bronchial epithelial cell-based malignant transformation model to explore the function of hsa-miR-200 family in the progress of PM2.5-induced lung cancer development.
Environ Pollut
; 319: 120981, 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36587786
20.
Diesel exhaust particles exposure induces liver dysfunction: Exploring predictive potential of human circulating microRNAs signature relevant to liver injury risk.
J Hazard Mater
; 458: 132060, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454487