Strong Quantum Metrological Limit from Many-Body Physics.

Surpassing the standard quantum limit and even reaching the Heisenberg limit using quantum entanglement, represents the Holy Grail of quantum metrology. However, quantum entanglement is a valuable resource that does not come without a price. The exceptional time overhead for the preparation of large-scale entangled states raises disconcerting concerns about whether the Heisenberg limit is fundamentally achievable. Here, we find a universal speed limit set by the Lieb-Robinson light cone for the quantum Fisher information growth to characterize the metrological potential of quantum resource states during their preparation. Our main result establishes a strong precision limit of quantum metrology accounting for the complexity of many-body quantum resource state preparation and reveals a fundamental constraint for reaching the Heisenberg limit in a generic many-body lattice system with bounded one-site energy. It enables us to identify the essential features of quantum many-body systems that are crucial for achieving the quantum advantage of quantum metrology, and brings an interesting connection between many-body quantum dynamics and quantum metrology.

An Efficient Agrobacterium rhizogenes-Mediated Hairy Root Transformation Method in a Soybean Root Biology Study.

The stable genetic transformation of soybean is time-consuming and inefficient. As a simple and practical alternative method, hairy root transformation mediated by Agrobacterium rhizogenes is widely applied in studying root-specific processes, nodulation, biochemical and molecular functions of genes of interest, gene editing efficiency of CRISPR/Cas9, and biological reactors and producers. Therefore, many laboratories have developed unique protocols to obtain hairy roots in composite plants composed of transgenic roots and wild-type shoots. However, these protocols still suffer from the shortcomings of low efficiency and time, space, and cost consumption. To address this issue, we developed a new protocol efficient regeneration and transformation of hairy roots (eR&T) in soybean, by integrating and optimizing the main current methods to achieve high efficiency in both hairy root regeneration and transformation within a shorter period and using less space. By this eR&T method, we obtained 100% regeneration of hairy roots for all explants, with an average 63.7% of transformation frequency, which promoted the simultaneous and comparative analysis of the function of several genes. The eR&T was experimentally verified Promoter:GUS reporters, protein subcellular localization, and CRISPR/Cas9 gene editing experiments. Employing this approach, we identified several novel potential regulators of nodulation, and nucleoporins of the Nup107-160 sub-complex, which showed development-dependent and tissue-dependent expression patterns, indicating their important roles in nodulation in soybean. Thus, the new eR&T method is an efficient and economical approach for investigating not only root and nodule biology, but also gene function.

Experimental demonstration of topological bounds in quantum metrology.

Quantum metrology is deeply connected to quantum geometry, through the fundamental notion of quantum Fisher information. Inspired by advances in topological matter, it was recently suggested that the Berry curvature and Chern numbers of band structures can dictate strict lower bounds on metrological properties, hence establishing a strong connection between topology and quantum metrology. In this work, we provide a first experimental verification of such topological bounds, by performing optimal quantum multi-parameter estimation and achieving the best possible measurement precision. By emulating the band structure of a Chern insulator, we experimentally determine the metrological potential across a topological phase transition, and demonstrate strong enhancement in the topologically non-trivial regime. Our work opens the door to metrological applications empowered by topology, with potential implications for quantum many-body systems.