Detalhe da pesquisa
1.
CD36 inhibition reduces non-small-cell lung cancer development through AKT-mTOR pathway.
Cell Biol Toxicol
; 40(1): 10, 2024 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38319449
2.
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.
Acta Pharmacol Sin
; 44(2): 308-320, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948752
3.
Fisetin treatment alleviates kidney injury in mice with diabetes-exacerbated atherosclerosis through inhibiting CD36/fibrosis pathway.
Acta Pharmacol Sin
; 44(10): 2065-2074, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37225845
4.
NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity.
J Biol Chem
; 296: 100624, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33812996
5.
Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression.
J Biol Chem
; 295(47): 15870-15882, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913121
6.
Novel 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-indene-4-thiol derivatives as potent selective human monoamine oxidase B inhibitors: Design, SAR development, and biological evaluation.
Bioorg Med Chem Lett
; 43: 128051, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887441
7.
Design, synthesis and anticancer activities of novel dual poly(ADP-ribose) polymerase-1/histone deacetylase-1 inhibitors.
Bioorg Med Chem Lett
; 30(8): 127036, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32088129
8.
Discovery of novel 2,3-dihydro-1H-inden-1-amine derivatives as selective monoamine oxidase B inhibitors.
Bioorg Med Chem Lett
; 29(9): 1090-1093, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833108
9.
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure.
Bioorg Med Chem Lett
; 29(8): 1012-1018, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30792039
10.
Identification of human telomerase inhibitors having the core of N-acyl-4,5-dihydropyrazole with anticancer effects.
Bioorg Med Chem Lett
; 26(6): 1508-1511, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26883149
11.
Novel tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one: Design, synthesis, model and use as hMAO-B inhibitors.
Bioorg Med Chem
; 24(8): 1741-8, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26964672
12.
Discovery and pharmacophore studies of novel pyrazole-based anti-melanoma agents.
Chem Biodivers
; 12(1): 116-32, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641840
13.
Targeting recruitment of disruptor of telomeric silencing 1-like (DOT1L): characterizing the interactions between DOT1L and mixed lineage leukemia (MLL) fusion proteins.
J Biol Chem
; 288(42): 30585-30596, 2013 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23996074
14.
Inhibition of Nogo-B reduces the progression of pancreatic cancer by regulation NF-κB/GLUT1 and SREBP1 pathways.
iScience
; 27(5): 109741, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38706871
15.
Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives.
J Med Chem
; 66(8): 5332-5363, 2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037122
16.
Discovery of Polo-like Kinase 4 Inhibitors for the Treatment of Cancer: A Mini Patent Review.
Mini Rev Med Chem
; 23(1): 67-79, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35657046
17.
Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-κB Pathway.
Nutrients
; 15(9)2023 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37432306
18.
Hydroxypropyl-ß-cyclodextrin inhibits the development of triple negative breast cancer by enhancing antitumor immunity.
Int Immunopharmacol
; 125(Pt A): 111168, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939513
19.
Overexpression of NgBR inhibits high-fat diet-induced atherosclerosis in ApoE-deficiency mice.
Hepatol Commun
; 7(4)2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996002
20.
PDB ligand conformational energies calculated quantum-mechanically.
J Chem Inf Model
; 52(3): 739-56, 2012 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22303903