Detalhe da pesquisa
1.
KEAP1-Mutant Lung Cancers Weaken Anti-Tumor Immunity and Promote an M2-like Macrophage Phenotype.
Int J Mol Sci
; 25(6)2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542481
2.
Ocular injury progression and cornea histopathology from chloropicrin vapor exposure: Relevant clinical biomarkers in mice.
Exp Eye Res
; 230: 109440, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933694
3.
The Novel RXR Agonist MSU-42011 Differentially Regulates Gene Expression in Mammary Tumors of MMTV-Neu Mice.
Int J Mol Sci
; 24(5)2023 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36901727
4.
Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing.
J Pharmacol Exp Ther
; 361(2): 259-267, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28280124
5.
Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria.
Malar J
; 16(1): 463, 2017 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29137631
6.
Design, synthesis, and biological activity of second-generation synthetic oleanane triterpenoids.
Org Biomol Chem
; 15(28): 6001-6005, 2017 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678272
7.
The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer.
Carcinogenesis
; 37(12): 1170-1179, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27659181
8.
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.
Nat Rev Cancer
; 7(5): 357-69, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17446857
9.
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.
Carcinogenesis
; 36(7): 769-81, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25939751
10.
Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
Pharmacol Res
; 100: 135-47, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26238177
11.
Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.
Pharmacol Rev
; 64(4): 972-1003, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22966038
12.
Synthesis and biological evaluation of amino acid methyl ester conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid against the production of nitric oxide (NO).
Bioorg Med Chem Lett
; 24(2): 532-4, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24388806
13.
An efficient synthesis of methyl 2-cyano-3,12-dioxoursol-1,9-dien-28-oate (CDDU-methyl ester): analogues, biological activities, and comparison with oleanolic acid derivatives.
Org Biomol Chem
; 12(28): 5192-200, 2014 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24915424
14.
The synthetic triterpenoid (CDDO-Im) inhibits STAT3, as well as IL-17, and improves DSS-induced colitis in mice.
Inflammopharmacology
; 22(6): 341-9, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24715223
15.
The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.
Carcinogenesis
; 34(1): 199-210, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23042302
16.
Retinoid X Receptor agonists as selective modulators of the immune system for the treatment of cancer.
Pharmacol Ther
; 252: 108561, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37952906
17.
The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis.
Mol Cells
; 46(3): 176-186, 2023 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36994476
18.
Adipocyte-derived kynurenine stimulates malignant transformation of mammary epithelial cells through the aryl hydrocarbon receptor.
Biochem Pharmacol
; 216: 115763, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37625554
19.
The Triterpenoid CDDO-Methyl Ester Redirects Macrophage Polarization and Reduces Lung Tumor Burden in a Nrf2-Dependent Manner.
Antioxidants (Basel)
; 12(1)2023 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36670978
20.
Exploring structural effects in a new class of NRF2 inhibitors.
RSC Med Chem
; 14(1): 74-84, 2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36760735