Detalhe da pesquisa
1.
Preclinical Characterization and Human Microdose Pharmacokinetics of ITMN-8187, a Nonmacrocyclic Inhibitor of the Hepatitis C Virus NS3 Protease.
Antimicrob Agents Chemother
; 61(1)2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27795376
2.
A 24-Week, Phase IIa, Randomized, Double-Blind, Placebo-Controlled Study of Ziritaxestat in Early Diffuse Cutaneous Systemic Sclerosis.
Arthritis Rheumatol
; 75(8): 1434-1444, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787101
3.
Virologic escape during danoprevir (ITMN-191/RG7227) monotherapy is hepatitis C virus subtype dependent and associated with R155K substitution.
Antimicrob Agents Chemother
; 56(1): 271-9, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22064535
4.
Antiviral activity of danoprevir (ITMN-191/RG7227) in combination with pegylated interferon α-2a and ribavirin in patients with hepatitis C.
J Infect Dis
; 204(4): 601-8, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21791662
5.
Danoprevir monotherapy decreases inflammatory markers in patients with chronic hepatitis C virus infection.
Antimicrob Agents Chemother
; 55(7): 3125-32, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21502634
6.
Preclinical characteristics of the hepatitis C virus NS3/4A protease inhibitor ITMN-191 (R7227).
Antimicrob Agents Chemother
; 52(12): 4432-41, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18824605
7.
Sequence and phenotypic analysis for resistance monitoring in hepatitis C virus drug development: recommendations from the HCV DRAG.
Gastroenterology
; 140(3): 755-60, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21255574
8.
Isolation and solubilization of proteins after TRIzol extraction of RNA and DNA from patient material following prolonged storage.
Biotechniques
; 42(4): 467-70, 472, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17489233
9.
Correction of SMN2 Pre-mRNA splicing by antisense U7 small nuclear RNAs.
Mol Ther
; 12(6): 1013-22, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16226920
10.
Commitment to splice site pairing coincides with A complex formation.
Mol Cell
; 15(3): 477-83, 2004 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-15304226