Detalhe da pesquisa
1.
Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol Cell
; 59(2): 258-69, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186291
2.
The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc Natl Acad Sci U S A
; 116(19): 9333-9339, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31019074
3.
Transcription with a laser: Radiation-damage-free diffraction of RNA Polymerase II crystals.
Methods
; 159-160: 23-28, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31029767
4.
Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.
Proc Natl Acad Sci U S A
; 111(23): 8470-5, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24872454
5.
Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc Natl Acad Sci U S A
; 111(48): 17122-7, 2014 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25362050
6.
Novel 1H-pyrazole-3-carboxamide derivatives: synthesis, anticancer evaluation and identification of their DNA-binding interaction.
Chem Pharm Bull (Tokyo)
; 62(3): 238-46, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24365978
7.
Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 Å using a free-electron laser.
bioRxiv
; 2023 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37790421
8.
Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate.
Mol Ther Oncolytics
; 31: 100726, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37771390
9.
Design, synthesis and biological evaluation of ß-carboline derivatives as novel inhibitors targeting B-Raf kinase.
Bioorg Med Chem Lett
; 22(14): 4783-6, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22704238
10.
Synthesis and structure of the ß-carboline derivatives and their binding intensity with cyclin-dependent kinase 2.
Chem Pharm Bull (Tokyo)
; 60(4): 435-41, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22466726
11.
Detection of Microcrystals for CryoEM.
Methods Mol Biol
; 2215: 299-307, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33368010
12.
A facile synthesis of 3-substituted 9H-pyrido[3,4-b]indol-1(2H)-one derivatives from 3-substituted beta-carbolines.
Molecules
; 15(8): 5680-91, 2010 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20717074
13.
(N-{[4-(1,3-benzothiazol-2-yl)anilino]carbonylmethyl-kappaO}iminodiacetato-kappa(3)O,N,O')(1,10-phenanthroline-kappa(2)N,N')cobalt(II) pentahydrate.
Acta Crystallogr C
; 64(Pt 4): m179-81, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18391383
14.
Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia.
J Med Chem
; 61(4): 1499-1518, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29357250
15.
MicroED Structure of Au146(p-MBA)57 at Subatomic Resolution Reveals a Twinned FCC Cluster.
J Phys Chem Lett
; 8(22): 5523-5530, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29072840
16.
Transmission electron microscopy for the evaluation and optimization of crystal growth.
Acta Crystallogr D Struct Biol
; 72(Pt 5): 603-15, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27139624
17.
[Treatment of second primary malignant tumor induced by radiotherapy].
Zhonghua Zhong Liu Za Zhi
; 25(3): 275-7, 2003 May.
Artigo
em Zh
| MEDLINE | ID: mdl-12839694
18.
A selectivity study on mTOR/PI3Kα inhibitors by homology modeling and 3D-QSAR.
J Mol Model
; 18(1): 171-86, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21523553