Pesquisa | Biblioteca Virtual em Saúde

1.

Low-dose metformin targets the lysosomal AMPK pathway through PEN2.

Ma, Teng; Tian, Xiao; Zhang, Baoding; Li, Mengqi; Wang, Yu; Yang, Chunyan; Wu, Jianfeng; Wei, Xiaoyan; Qu, Qi; Yu, Yaxin; Long, Shating; Feng, Jin-Wei; Li, Chun; Zhang, Cixiong; Xie, Changchuan; Wu, Yaying; Xu, Zheni; Chen, Junjie; Yu, Yong; Huang, Xi; He, Ying; Yao, Luming; Zhang, Lei; Zhu, Mingxia; Wang, Wen; Wang, Zhi-Chao; Zhang, Mingliang; Bao, Yuqian; Jia, Weiping; Lin, Shu-Yong; Ye, Zhiyun; Piao, Hai-Long; Deng, Xianming; Zhang, Chen-Song; Lin, Sheng-Cai.

Nature ; 603(7899): 159-165, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35197629

2.

ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.

Li, Terytty Yang; Sun, Yu; Liang, Yu; Liu, Qing; Shi, Yuzhe; Zhang, Chen-Song; Zhang, Cixiong; Song, Lintao; Zhang, Pu; Zhang, Xianzhong; Li, Xiaotong; Chen, Tao; Huang, Hui-Ying; He, Xiadi; Wang, Yi; Wu, Yu-Qing; Chen, Shaoxuan; Jiang, Ming; Chen, Canhe; Xie, Changchuan; Yang, James Y; Lin, Yan; Zhao, Shimin; Ye, Zhiyun; Lin, Shu-Yong; Chiu, Daniel Tsun-Yee; Lin, Sheng-Cai.

Mol Cell ; 62(3): 359-370, 2016 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-27153534

3.

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.

Zhang, Chen-Song; Hawley, Simon A; Zong, Yue; Li, Mengqi; Wang, Zhichao; Gray, Alexander; Ma, Teng; Cui, Jiwen; Feng, Jin-Wei; Zhu, Mingjiang; Wu, Yu-Qing; Li, Terytty Yang; Ye, Zhiyun; Lin, Shu-Yong; Yin, Huiyong; Piao, Hai-Long; Hardie, D Grahame; Lin, Sheng-Cai.

Nature ; 548(7665): 112-116, 2017 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-28723898

4.

Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury.

Sun, Yu; Li, Terytty Yang; Song, Lintao; Zhang, Cixiong; Li, Jingyi; Lin, Zhi-Zhong; Lin, Sheng-Cai; Lin, Shu-Yong.

Hepatology ; 67(6): 2397-2413, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29272037

5.

Mechanism and physiological significance of growth factor-related autophagy.

Li, Terytty Yang; Lin, Shu-Yong; Lin, Sheng-Cai.

Physiology (Bethesda) ; 28(6): 423-31, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24186937

6.

Reply.

Sun, Yu; Lin, Shu-Yong.

Hepatology ; 67(6): 2477, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29389009

7.

Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.

Wu, Han-Ming; Yang, Yang Vivian; Huang, Na-Jun; Fan, Li-Ping; Dai, Ying-Ying; Hu, Ke-Ting; Tang, Tian-Yu; Liu, Lin; Xu, Yue; Liu, Dong-Tai; Cai, Ze-Xin; Niu, Xiao-Yu; Ren, Xin-Yi; Yao, Zheng-Hao; Qin, Hao-Yu; Chen, Jian-Zhen; Huang, Xi; Zhang, Cixiong; You, Xiang; Wang, Chen; He, Ying; Hong, Wei; Sun, Yu-Xia; Zhan, Yi-Hong; Lin, Shu-Yong.

Front Neurosci ; 18: 1368552, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38716255

8.

AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine.

Li, Mengqi; Wang, Yu; Wei, Xiaoyan; Cai, Wei-Feng; Wu, Jianfeng; Zhu, Mingxia; Wang, Yongliang; Liu, Yan-Hui; Xiong, Jinye; Qu, Qi; Chen, Yan; Tian, Xiao; Yao, Luming; Xie, Renxiang; Li, Xiaomin; Chen, Siwei; Huang, Xi; Zhang, Cixiong; Xie, Changchuan; Wu, Yaying; Xu, Zheni; Zhang, Baoding; Jiang, Bin; Wang, Zhi-Chao; Li, Qinxi; Li, Gang; Lin, Shu-Yong; Yu, Li; Piao, Hai-Long; Deng, Xianming; Han, Jiahuai; Zhang, Chen-Song; Lin, Sheng-Cai.

Cell Res ; 2024 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-38898113

9.

Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.

Wu, Yu-Qing; Zhang, Chen-Song; Xiong, Jinye; Cai, Dong-Qi; Wang, Chen-Zhe; Wang, Yu; Liu, Yan-Hui; Wang, Yu; Li, Yiming; Wu, Jian; Wu, Jianfeng; Lan, Bin; Wang, Xuefeng; Chen, Siwei; Cao, Xianglei; Wei, Xiaoyan; Hu, Hui-Hui; Guo, Huiling; Yu, Yaxin; Ghafoor, Abdul; Xie, Changchuan; Wu, Yaying; Xu, Zheni; Zhang, Cixiong; Zhu, Mingxia; Huang, Xi; Sun, Xiufeng; Lin, Shu-Yong; Piao, Hai-Long; Zhou, Jianyin; Lin, Sheng-Cai.

Cell Res ; 33(11): 835-850, 2023 11.

Artigo em Inglês | MEDLINE | ID: mdl-37726403

10.

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.

Zhang, Chen-Song; Li, Mengqi; Wang, Yu; Li, Xiaoyang; Zong, Yue; Long, Shating; Zhang, Mingliang; Feng, Jin-Wei; Wei, Xiaoyan; Liu, Yan-Hui; Zhang, Baoding; Wu, Jianfeng; Zhang, Cixiong; Lian, Wenhua; Ma, Teng; Tian, Xiao; Qu, Qi; Yu, Yaxin; Xiong, Jinye; Liu, Dong-Tai; Wu, Zhenhua; Zhu, Mingxia; Xie, Changchuan; Wu, Yaying; Xu, Zheni; Yang, Chunyan; Chen, Junjie; Huang, Guohong; He, Qingxia; Huang, Xi; Zhang, Lei; Sun, Xiufeng; Liu, Qingfeng; Ghafoor, Abdul; Gui, Fu; Zheng, Kaili; Wang, Wen; Wang, Zhi-Chao; Yu, Yong; Zhao, Qingliang; Lin, Shu-Yong; Wang, Zhi-Xin; Piao, Hai-Long; Deng, Xianming; Lin, Sheng-Cai.

Nat Metab ; 4(10): 1369-1401, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36217034

11.

SRC promotes lipogenesis: implications for obesity and breast cancer.

Lin, Shu-Yong; Lin, Sheng-Cai.

Mol Cell Oncol ; 8(1): 1866975, 2021 Jan 12.

Artigo em Inglês | MEDLINE | ID: mdl-33553613

12.

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.

Shi, Meng; Huang, Xiao-Yu; Ren, Xin-Yi; Wei, Xiao-Yan; Ma, Yue; Lin, Zhi-Zhong; Liu, Dong-Tai; Song, Lintao; Zhao, Tong-Jin; Li, Guang; Yao, Luming; Zhu, Mingxia; Zhang, Cixiong; Xie, Changchuan; Wu, Yaying; Wu, Han-Ming; Fan, Li-Ping; Ou, Jingxing; Zhan, Yi-Hong; Lin, Shu-Yong; Lin, Sheng-Cai.

Nat Cell Biol ; 23(3): 268-277, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33664495

13.

Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.

Song, Lintao; Liu, Zhihua; Hu, Hui-Hui; Yang, Ying; Li, Terytty Yang; Lin, Zhi-Zhong; Ye, Jing; Chen, Jianing; Huang, Xi; Liu, Dong-Tai; Zhou, Jing; Shi, Yiran; Zhao, Hao; Xie, Changchuan; Chen, Lanfen; Song, Erwei; Lin, Shu-Yong; Lin, Sheng-Cai.

Nat Commun ; 11(1): 5842, 2020 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-33203880

14.

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress.

Zong, Yue; Zhang, Chen-Song; Li, Mengqi; Wang, Wen; Wang, Zhichao; Hawley, Simon A; Ma, Teng; Feng, Jin-Wei; Tian, Xiao; Qi, Qu; Wu, Yu-Qing; Zhang, Cixiong; Ye, Zhiyun; Lin, Shu-Yong; Piao, Hai-Long; Hardie, D Grahame; Lin, Sheng-Cai.

Cell Res ; 29(6): 460-473, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30948787

15.

Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.

Li, Mengqi; Zhang, Chen-Song; Zong, Yue; Feng, Jin-Wei; Ma, Teng; Hu, Meiqin; Lin, Zhizhong; Li, Xiaotong; Xie, Changchuan; Wu, Yaying; Jiang, Dong; Li, Ying; Zhang, Cixiong; Tian, Xiao; Wang, Wen; Yang, Yanyan; Chen, Jie; Cui, Jiwen; Wu, Yu-Qing; Chen, Xin; Liu, Qing-Feng; Wu, Jianfeng; Lin, Shu-Yong; Ye, Zhiyun; Liu, Ying; Piao, Hai-Long; Yu, Li; Zhou, Zhuan; Xie, Xiao-Song; Hardie, D Grahame; Lin, Sheng-Cai.

Cell Metab ; 30(3): 508-524.e12, 2019 09 03.

Artigo em Inglês | MEDLINE | ID: mdl-31204282

16.

Carbohydrates: Not All that Bad?

Lin, Shu-Yong; Zhang, Chen-Song; Lin, Sheng-Cai.

Cell Metab ; 28(5): 671-672, 2018 11 06.

Artigo em Inglês | MEDLINE | ID: mdl-30403985

17.

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.

Li, Terytty Yang; Song, Lintao; Sun, Yu; Li, Jingyi; Yi, Cong; Lam, Sin Man; Xu, Dijin; Zhou, Linkang; Li, Xiaotong; Yang, Ying; Zhang, Chen-Song; Xie, Changchuan; Huang, Xi; Shui, Guanghou; Lin, Shu-Yong; Reue, Karen; Lin, Sheng-Cai.

Nat Commun ; 9(1): 1916, 2018 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-29765047

18.

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.

Luo, Hui; Jiang, Ming; Lian, Guili; Liu, Qing; Shi, Meng; Li, Terytty Yang; Song, Lintao; Ye, Jing; He, Ying; Yao, Luming; Zhang, Cixiong; Lin, Zhi-Zhong; Zhang, Chen-Song; Zhao, Tong-Jin; Jia, Wei-Ping; Li, Peng; Lin, Shu-Yong; Lin, Sheng-Cai.

Cell Metab ; 27(4): 843-853.e6, 2018 04 03.

Artigo em Inglês | MEDLINE | ID: mdl-29617643

19.

C-terminus of MUC16 activates Wnt signaling pathway through its interaction with ß-catenin to promote tumorigenesis and metastasis.

Liu, Qi; Cheng, Zhen; Luo, Lianzhong; Yang, Yun; Zhang, Zhenzhu; Ma, Huanhuan; Chen, Tao; Huang, Xi; Lin, Shu-Yong; Jin, Meijun; Li, Qinxi; Li, Xiaotong.

Oncotarget ; 7(24): 36800-36813, 2016 Jun 14.

Artigo em Inglês | MEDLINE | ID: mdl-27167110

20.

RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.

Zhang, Chen-Song; Liu, Qi; Li, Mengqi; Lin, Shu-Yong; Peng, Yongying; Wu, Di; Li, Terytty Yang; Fu, Qiang; Jia, Weiping; Wang, Xinjun; Ma, Teng; Zong, Yue; Cui, Jiwen; Pu, Chengfei; Lian, Guili; Guo, Huiling; Ye, Zhiyun; Lin, Sheng-Cai.

Cell Res ; 25(9): 1025-42, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26215701

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