Detalhe da pesquisa
1.
Selective inhibition of physiological late Na+ current stabilizes ventricular repolarization.
Am J Physiol Heart Circ Physiol
; 314(2): H236-H245, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28971840
2.
Combined actions of ivabradine and ranolazine reduce ventricular rate during atrial fibrillation.
J Cardiovasc Electrophysiol
; 26(3): 329-35, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25346368
3.
Selective inhibition of the late sodium current has no adverse effect on electrophysiological or contractile function of the normal heart.
J Cardiovasc Pharmacol
; 63(6): 512-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24406487
4.
A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias.
J Pharmacol Exp Ther
; 344(1): 23-32, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23010360
5.
Differential conditions for early after-depolarizations and triggered activity in cardiomyocytes derived from transgenic LQT1 and LQT2 rabbits.
J Physiol
; 590(5): 1171-80, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22183728
6.
Phytosterol accumulation results in ventricular arrhythmia, impaired cardiac function and death in mice.
Sci Rep
; 11(1): 17449, 2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34465831
7.
Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1.
Mol Biol Cell
; 17(1): 146-54, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16251351
8.
The phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1.
Mol Cell Biol
; 25(9): 3630-8, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831468
9.
The novel late Na+ current inhibitor, GS-6615 (eleclazine) and its anti-arrhythmic effects in rabbit isolated heart preparations.
Br J Pharmacol
; 173(21): 3088-3098, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27449698
10.
Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.
J Med Chem
; 59(19): 9005-9017, 2016 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27690427
11.
Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ Cycling.
PLoS One
; 10(5): e0122754, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25970695
12.
If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation.
Heart Rhythm
; 11(12): 2288-96, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25111327
13.
Correction: Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ Cycling.
PLoS One
; 10(7): e0132198, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26131559
14.
Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G alpha o* protein.
Am J Physiol Heart Circ Physiol
; 294(3): H1335-47, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18192223
15.
Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.
Am J Physiol Heart Circ Physiol
; 291(2): H543-51, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16501027
16.
Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5.
Am J Physiol Heart Circ Physiol
; 287(2): H681-90, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15277200