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1.
Br J Neurosurg ; 36(2): 280-283, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30317888

RESUMO

Schwannomas are peripheral nerve tumours that are uncommon. They typical present with a palpable mass, pain or neurological changes. We describe a saphenous nerve schwannoma compressing the superficial femoral artery and causing vascular claudication. We also review the literature.


Assuntos
Neurilemoma , Neoplasias do Sistema Nervoso Periférico , Humanos , Neurilemoma/complicações , Neurilemoma/diagnóstico por imagem , Neurilemoma/cirurgia , Neoplasias do Sistema Nervoso Periférico/diagnóstico , Neoplasias do Sistema Nervoso Periférico/diagnóstico por imagem , Coxa da Perna/inervação
2.
Eur Spine J ; 24 Suppl 4: S465-71, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-24908254

RESUMO

INTRODUCTION: Pigmented Villonodular synovitis (PVNS) is a rare vertebral pathology--around 50 reports, only 3 concerning C1-C2 location. CASE REPORT: A 64-year-old man, submitted to a right nephrectomy for a clear cell carcinoma, presented with an asymptomatic osteolytic C1-C2 lesion. Even though the diagnosis of metastatic disease was the most probable, the presence of a solitary lesion without other osseous or systemic localization and the predicted low risk of recurrence imposed a surgical biopsy. A pigmented villonodular synovitis diagnosis was made, a rare vertebral pathology--around 50 reports, only 3 concerning C1-C2 location. No further treatment was assigned precluding the iatrogenic consequences of empirical treatments based on clinical diagnosis with no histopathological support. The patient remains stable at 18 months of follow-up. CONCLUSION: A large differential diagnosis should be made when the typical findings for metastatic disease are absent precluding the iatrogenic consequences of empirical treatments based on clinical diagnosis with no histopathological support.


Assuntos
Adenocarcinoma de Células Claras/complicações , Vértebras Cervicais , Neoplasias Renais/complicações , Doenças Raras/diagnóstico , Sinovite Pigmentada Vilonodular/diagnóstico , Adenocarcinoma de Células Claras/diagnóstico , Adenocarcinoma de Células Claras/secundário , Diagnóstico Diferencial , Humanos , Neoplasias Renais/patologia , Masculino , Pessoa de Meia-Idade , Doenças Raras/complicações , Sinovite Pigmentada Vilonodular/complicações
3.
CNS Oncol ; 11(2): CNS85, 2022 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-35535978

RESUMO

Primary breast sarcomas are rare high-grade tumors with a reported incidence of <1% of breast malignancies. Its dissemination to the CNS is exceptional and only one is found in the literature. The authors described the case of a 22-year-old female with history of a breast undifferentiated sarcoma that present with two large bilateral retrolenticular brain metastases. Both lesions were excised in the same procedure and she underwent adjuvant therapy. She died 24 months after surgery. Despite being aggressive lesions, aggressive treatment of primary breast sarcomas including brain metastases excision, should be considered in order to improve overall survival.


Assuntos
Neoplasias Encefálicas , Neoplasias da Mama , Sarcoma , Adulto , Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/cirurgia , Neoplasias da Mama/patologia , Terapia Combinada , Feminino , Humanos , Sarcoma/diagnóstico por imagem , Sarcoma/cirurgia , Adulto Jovem
4.
Port J Card Thorac Vasc Surg ; 28(1): 61-63, 2021 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-33834648

RESUMO

Pancoast tumours are defined as tumours arising from the upper lobe and invading the thoracic inlet,representing less than 5% of all lung cancers. Clinical features depend on the involved structures. For many years invasion of the spine was considered unresectable and fatal. Due to the progress in spine surgery, en bloc resection including the spine is nowadays possible. We report the first case of a successful en bloc vertebral resection of a Pancoast tumour in a 66 year-old male, with a squamous cell carcinoma, treated at our department in a multidisciplinary setting, after induction chemoradiotherapy. An en bloc resection including the left upper lobe, the first three ribs and the vertebral body of D2, was performed through a Paulson incision after posterior cervico-dorsal arthrodesis. A complete R0 resection was confirmed on the pathology specimen. Currently, one year after surgery, although no local recurrence has occurred, the patient is being treated with immunotherapy due to disease progression in the right acetabulum which was irradiated (20Gy) and then submitted to iliac resection and prothesis reconstruction.


Assuntos
Neoplasias Pulmonares , Síndrome de Pancoast , Idoso , Humanos , Neoplasias Pulmonares/cirurgia , Masculino , Recidiva Local de Neoplasia , Síndrome de Pancoast/diagnóstico por imagem , Síndrome de Pancoast/cirurgia
5.
Acta Med Port ; 32(6): 466-468, 2019 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-31292029

RESUMO

Fibrous dysplasia is a bone disease characterized by an osteoblastic dysfunction resulting in a fibrous replacement of the normal medullary bone. We describe the case of a 33-year-old who presented with low back pain irradiating to her right leg. Both the computed tomography scan and magnetic resonance imaging showed an osteolytic, multicystic lesion of the right hemi-sacrum with invasion of the right S1 foramen. She underwent foraminotomy and curettage of the lesion. Histological diagnosis was fibrous dysplasia, without features of malignant transformation. Three years after surgery the patient is asymptomatic and imaging is stable. This is the fifth known case of monostotic fibrous dysplasia involving the sacrum, a rare entity that must be considered in the differential diagnosis when approaching patients with sacral lesions.


A displasia fibrosa é uma doença óssea caracterizada por uma disfunção osteoblástica que resulta na substituição do osso medular normal por tecido fibroso. Descrevemos o caso de uma doente de 33 anos que se apresentou com lombalgia e ciatalgia direita. A tomografia computorizada e ressonância magnética lombares revelaram uma lesão osteolítica e multiquística no hemissacro direito com invasão do foramen de S1. A doente foi submetida a foraminotomia e curetagem da lesão. O diagnóstico histológico foi de displasia fibrosa, sem sinais de transformação maligna. Três anos após a cirurgia, a doente está assintomática e os estudos de imagem apresentam estabilidade da lesão. Este é o quinto caso conhecido na literatura de displasia fibrosa monostótica com atingimento do sacro, uma entidade rara que deve ser considerada no diagnóstico diferencial de doentes com lesões do sacro.


Assuntos
Displasia Fibrosa Monostótica/complicações , Dor Lombar/etiologia , Doenças Raras/complicações , Sacro , Adulto , Feminino , Displasia Fibrosa Monostótica/diagnóstico por imagem , Displasia Fibrosa Monostótica/cirurgia , Humanos , Dor Lombar/cirurgia , Imageamento por Ressonância Magnética , Radiculopatia/etiologia , Doenças Raras/diagnóstico por imagem , Doenças Raras/cirurgia , Sacro/diagnóstico por imagem , Sacro/cirurgia , Tomografia Computadorizada por Raios X
7.
CNS Oncol ; 6(2): 107-110, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-28425761

RESUMO

Astrocytomas are responsible for 30% of all primitive intramedullary tumors with cervicothoracic predominance. However, only about one hundred cases of intramedullary pilocytic astrocytomas were described. The authors described the case of a 69 year-old patient presenting with a broad-base gait, bilateral pain and dysesthesia of inferior limbs with a diagnosis of an intra-axial cystic lesion centered to the conus medullaris, diagnosed as pilocytic astrocytoma of conus medullaris (PACM) after surgery. To the best of our knowledge, only two previous reports concerning PACM were made. As benign lesions associated with long survivals, function should be the mainstay of treatment of PACM. Surgical resection should be performed. Adjuvant radiotherapy or chemotherapy has no establish role in pilocytic astrocytic lesions.


Assuntos
Astrocitoma/diagnóstico por imagem , Astrocitoma/cirurgia , Neoplasias da Medula Espinal/diagnóstico por imagem , Neoplasias da Medula Espinal/cirurgia , Medula Espinal/patologia , Idoso , Astrocitoma/diagnóstico , Feminino , Humanos , Imageamento por Ressonância Magnética , Medula Espinal/cirurgia , Neoplasias da Medula Espinal/diagnóstico
8.
Surg Neurol Int ; 7(Suppl 38): S908-S910, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-28028446

RESUMO

BACKGROUND: Myeloid sarcoma (MS) is a malignant tumor that usually occurs concomitantly with or following acute myeloid leukemia (AML). Cavernomas are benign congenital malformations that are unusual in the spine and exceedingly rare in pure extradural locations. CASE DESCRIPTION: We report a 73-year-old female with a previous medical history of AML in remission for 3 years who presented with symptoms of low back pain and right lower extremity radiculopathy. A magnetic resonance scan showed an extradural, foraminal lesion centered at the L2 level involving the right L2 nerve root. In view of the history of AML, this lesion was potentially considered MS, a form of AML relapse. Surgery consisting of a right L1 and L2 hemilaminectomy facilitated gross total resection of the purely extradural lesion the proved histologically to be a cavernoma. CONCLUSION: In patients with a history of leukemia, MS must be considered in the differential diagnosis for any epidural or nerve root lesion that appears following treatment. Although rare, cavernomas must be considered among the differential diagnoses for epidural nerve root lesions in the setting of AML.

9.
Int J Surg Pathol ; 23(5): 399-403, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25911563

RESUMO

Lipomatous meningioma is a very rare subtype of metaplastic meningioma. It is defined by the presence of adipocytic-like cells, which are thought to result from lipid accumulation in meningothelial cells or true metaplastic change. We report a case of a lipomatous meningioma arising in a female patient complaining of recent seizures. Imaging studies revealed a 4-cm dural-based mass, with severe perilesional edema. Histologically, the tumor was composed of meningothelial whorls intermixed with adipocytic-like cells. No atypical criteria or brain invasion were found. The 2 components have differences in progesterone receptor expression and Ki-67 labeling, which may suggest that adipocytic-like cells may represent some quiescent form of meningothelial neoplastic cells, characterized by metabolic abnormalities, leading to lipid accumulation and very low proliferative activity. Lipomatous meningioma should also be kept in mind when considering the differential diagnosis of dural lesions with vasogenic edema in the absence of brain invasion.


Assuntos
Lipídeos , Neoplasias Meníngeas/patologia , Meningioma/patologia , Biomarcadores Tumorais/metabolismo , Feminino , Humanos , Imageamento por Ressonância Magnética , Neoplasias Meníngeas/metabolismo , Meningioma/metabolismo , Pessoa de Meia-Idade
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