Detalhe da pesquisa
1.
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Nature
; 620(7975): 881-889, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558878
2.
Metabolic modulation of tumours with engineered bacteria for immunotherapy.
Nature
; 598(7882): 662-666, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616044
3.
Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.
J Biol Chem
; 291(25): 13014-27, 2016 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27056325
4.
Suppression of inflammation by a synthetic histone mimic.
Nature
; 468(7327): 1119-23, 2010 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21068722
5.
Suppression of TH17-mediated pathology through BET bromodomain inhibition.
Drug Discov Today Technol
; 19: 39-44, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27769356
6.
Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
bioRxiv
; 2023 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993446
7.
Engineering living therapeutics with synthetic biology.
Nat Rev Drug Discov
; 20(12): 941-960, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616030
8.
Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Ann N Y Acad Sci
; 1506(1): 98-117, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34786712
9.
Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.
Prostaglandins Other Lipid Mediat
; 92(1-4): 33-43, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20214997
10.
Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity.
Nat Commun
; 11(1): 2739, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483165
11.
Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema.
J Clin Invest
; 115(12): 3460-72, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16284650
12.
Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease.
Sci Rep
; 7: 43139, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28233801
13.
Antiinflammatory effects of bromodomain and extraterminal domain inhibition in cystic fibrosis lung inflammation.
JCI Insight
; 1(11)2016 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27517095
14.
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.
ACS Med Chem Lett
; 7(2): 145-50, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26985289
15.
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.
FEBS Lett
; 530(1-3): 73-8, 2002 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12387869
16.
BET bromodomain inhibition suppresses TH17-mediated pathology.
J Exp Med
; 210(11): 2181-90, 2013 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24101376
17.
Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress.
Aging Cell
; 7(4): 506-15, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18419796
18.
Cutting edge: Modulation of intestinal autoimmunity and IL-2 signaling by sphingosine kinase 2 independent of sphingosine 1-phosphate.
J Immunol
; 179(9): 5644-8, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17947634
19.
Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.
J Immunol
; 179(10): 7030-41, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17982094
20.
Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis.
J Immunol
; 179(3): 1740-50, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17641040