Detalhe da pesquisa
1.
Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.
J Antimicrob Chemother
; 77(6): 1625-1634, 2022 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245364
2.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc Natl Acad Sci U S A
; 116(14): 7015-7020, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894487
3.
Structure of acid deoxyribonuclease.
Nucleic Acids Res
; 45(10): 6217-6227, 2017 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28369538
4.
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Proc Natl Acad Sci U S A
; 113(30): E4357-66, 2016 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27357661
5.
Some of the most interesting CASP11 targets through the eyes of their authors.
Proteins
; 84 Suppl 1: 34-50, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26473983
6.
High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus.
J Infect Dis
; 212 Suppl 2: S167-71, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957961
7.
Crystal structures of Mycobacterial MeaB and MMAA-like GTPases.
J Struct Funct Genomics
; 16(2): 91-9, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25832174
8.
Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10.
Proteins
; 82 Suppl 2: 26-42, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24318984
9.
A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob Agents Chemother
; 58(3): 1458-67, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366729
10.
Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis.
Acta Crystallogr F Struct Biol Commun
; 80(Pt 4): 82-91, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656226
11.
Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis.
Acta Crystallogr F Struct Biol Commun
; 80(Pt 2): 43-51, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305785
12.
Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site.
Sci Rep
; 13(1): 6940, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37117205
13.
Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1.
Acta Crystallogr F Struct Biol Commun
; 79(Pt 10): 257-266, 2023 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37728609
14.
Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme.
Protein Sci
; 31(4): 882-899, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35048450
15.
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362.
J Med Chem
; 65(20): 14121-14143, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36216349
16.
Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 9): 1070-7, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21904052
17.
Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis.
Acta Crystallogr F Struct Biol Commun
; 77(Pt 2): 54-60, 2021 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620038
18.
Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1.
Sci Rep
; 11(1): 9453, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947893
19.
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
PLoS One
; 16(3): e0241738, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33760815
20.
Toward a structome of Acinetobacter baumannii drug targets.
Protein Sci
; 29(3): 789-802, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31930600