Detalhe da pesquisa
1.
P1' specificity of the S219V/R203G mutant tobacco etch virus protease.
Proteins
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38666764
2.
Structural basis for cell type specific DNA binding of C/EBPß: The case of cell cycle inhibitor p15INK4b promoter.
J Struct Biol
; 214(4): 107918, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343842
3.
Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases.
Int J Mol Sci
; 23(19)2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36232729
4.
Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.
Nucleic Acids Res
; 47(19): 10134-10150, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199869
5.
The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci
; 21(21)2020 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33171880
6.
Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew Chem Int Ed Engl
; 55(19): 5703-7, 2016 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27038327
7.
Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 5): 1102-11, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25945576
8.
Self-inhibited State of Venezuelan Equine Encephalitis Virus (VEEV) nsP2 Cysteine Protease: A Crystallographic and Molecular Dynamics Analysis.
J Mol Biol
; 435(6): 168012, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792007
9.
Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification.
RSC Chem Biol
; 4(5): 334-343, 2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37181631
10.
Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system.
Acta Crystallogr D Biol Crystallogr
; 68(Pt 3): 201-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22349221
11.
Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1.
Front Chem
; 10: 910953, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36051621
12.
Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy.
J Struct Biol
; 176(3): 292-301, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21963792
13.
Structure of human dual-specificity phosphatase 27 at 2.38â Å resolution.
Acta Crystallogr D Biol Crystallogr
; 67(Pt 5): 471-9, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21543850
14.
Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH.
Acta Crystallogr D Biol Crystallogr
; 67(Pt 7): 639-45, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21697602
15.
Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus.
PLoS One
; 16(3): e0248385, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784308
16.
Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites.
Chem Sci
; 12(11): 3876-3884, 2021 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34163656
17.
A rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH.
Bioorg Med Chem Lett
; 20(9): 2813-6, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20350805
18.
Development of antiproliferative phenylmaleimides that activate the unfolded protein response.
Bioorg Med Chem
; 18(12): 4535-41, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20472436
19.
Engineering of glycerol dehydrogenase for improved activity towards 1, 3-butanediol.
Appl Microbiol Biotechnol
; 88(1): 117-24, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20585771
20.
Crystallographic, spectroscopic, and computational analysis of a flavin C4a-oxygen adduct in choline oxidase.
Biochemistry
; 48(4): 720-8, 2009 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19133805