Detalhe da pesquisa
1.
PAH deficient pathology in humanized c.1066-11G>A phenylketonuria mice.
Hum Mol Genet
; 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38520741
2.
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Nature
; 560(7719): 441-446, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30111840
3.
CPEB4-CLOCK crosstalk during temporal lobe epilepsy.
Epilepsia
; 64(10): 2827-2840, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543852
4.
Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors.
Brain
; 144(7): 2009-2023, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33725094
5.
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease.
Acta Neuropathol
; 142(1): 159-177, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33934221
6.
Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism.
Brain
; 143(7): 2207-2219, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32533168
7.
Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy.
Brain
; 143(7): 2139-2153, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32594159
8.
Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease.
Int J Mol Sci
; 22(1)2021 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33466523
9.
High concordance between hippocampal transcriptome of the mouse intra-amygdala kainic acid model and human temporal lobe epilepsy.
Epilepsia
; 61(12): 2795-2810, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33070315
10.
Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome.
Neurobiol Dis
; 127: 210-222, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30831192
11.
The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation.
FASEB J
; 32(6): 3020-3032, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401585
12.
In vivo inhibition of the mitochondrial H+-ATP synthase in neurons promotes metabolic preconditioning.
EMBO J
; 33(7): 762-78, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24521670
13.
Pharmacokinetic evaluation of marbofloxacin after intravenous administration at different ages in llama crias, and pharmacokinetic/pharmacodynamic analysis by Monte Carlo simulation.
J Vet Pharmacol Ther
; 41(6): 861-870, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30020535
14.
Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease.
Hum Mol Genet
; 24(17): 5040-52, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26082469
15.
Regulation of proteasome activity by P2Y2 receptor underlies the neuroprotective effects of extracellular nucleotides.
Biochim Biophys Acta Mol Basis Dis
; 1863(1): 43-51, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768902
16.
The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
Acta Neuropathol
; 134(6): 839-850, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28861715
17.
Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
Hum Mol Genet
; 23(3): 767-81, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24064336
18.
Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system.
Acta Neuropathol
; 131(3): 411-25, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26646779
19.
Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice.
Metab Brain Dis
; 31(3): 579-86, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26666246
20.
α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.
Hum Mol Genet
; 21(3): 495-510, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22045698