Detalhe da pesquisa
1.
Large-scale mapping and mutagenesis of human transcriptional effector domains.
Nature
; 616(7956): 365-372, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37020022
2.
Mapping chromatin modifications at the single cell level.
Development
; 146(12)2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249006
3.
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
Proc Natl Acad Sci U S A
; 115(40): 10172-10177, 2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232263
4.
High-throughput discovery and characterization of viral transcriptional effectors in human cells.
Cell Syst
; 14(6): 482-500.e8, 2023 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37348463
5.
The H3.3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation.
bioRxiv
; 2023 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37873347
6.
High-throughput functional characterization of combinations of transcriptional activators and repressors.
Cell Syst
; 14(9): 746-763.e5, 2023 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543039
7.
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells.
Elife
; 112022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678392
8.
CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.
Neuron
; 104(2): 239-255.e12, 2019 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31422865
9.
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity.
Science
; 363(6428)2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30765536
10.
Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.
Stem Cell Reports
; 9(4): 1221-1233, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28966121
11.
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes.
Stem Cell Reports
; 9(6): 1745-1753, 2017 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29198827
12.
Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.
Sci Transl Med
; 9(385)2017 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28404863
13.
Memory regulatory T cells reside in human skin.
J Clin Invest
; 124(3): 1027-36, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24509084