Detalhe da pesquisa
1.
Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis.
Mol Cancer Ther
; 23(4): 492-506, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37796181
2.
miR-3132 upregulates surface TRAIL to induce apoptotic cell death in cancer cells.
Am J Cancer Res
; 12(1): 315-326, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35141020
3.
P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9.
Neoplasia
; 23(3): 304-325, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33582407
4.
LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers.
Oncogenesis
; 10(5): 40, 2021 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33990543
5.
Correction: Discovery and clinical introduction of first-in-class imipridone ONC201.
Oncotarget
; 12(21): 2231, 2021 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34676056
6.
CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.
Cell Cycle
; 17(5): 557-567, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28749203
7.
Role of Dopamine Receptors in the Anticancer Activity of ONC201.
Neoplasia
; 20(1): 80-91, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29216597
8.
ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer.
Mol Cancer Res
; 16(5): 754-766, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29588330
9.
Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.
Cell Cycle
; 17(4): 468-478, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29157092
10.
ONC201: a new treatment option being tested clinically for recurrent glioblastoma.
Transl Cancer Res
; 6(Suppl 7): S1239-S1243, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30175049
11.
Preclinical rationale for combination of crizotinib with mitomycin C for the treatment of advanced colorectal cancer.
Cancer Biol Ther
; 18(9): 694-704, 2017 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28886275
12.
miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells.
Cancer Res
; 77(24): 6902-6913, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061672
13.
Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP.
Oncotarget
; 8(47): 81776-81793, 2017 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29137221
14.
Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212.
Cell Cycle
; 16(19): 1790-1799, 2017 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28489985
15.
Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
PLoS One
; 12(8): e0180541, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28767654
16.
Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation.
Cancer Res
; 76(7): 1989-99, 2016 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26759239
17.
Discovery and clinical introduction of first-in-class imipridone ONC201.
Oncotarget
; 7(45): 74380-74392, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27602582
18.
Current treatment of early breast cancer: adjuvant and neoadjuvant therapy.
F1000Res
; 3: 198, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25400908
19.
Bcl-2 Protein Targeting by the p53/p21 Complex-Letter.
Cancer Res
; 78(10): 2770-2771, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29703721
20.
MMR-deficiency and BRCA2/EGFR/NTRK mutations.
Aging (Albany NY)
; 9(8): 1849-1850, 2017 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28783711