Detalhe da pesquisa
1.
Chemoprobe-based assays of histone lysine demethylase 1A target occupation enable in vivo pharmacokinetics and pharmacodynamics studies of KDM1A inhibitors.
J Biol Chem
; 294(20): 8311-8322, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804215
2.
Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis.
Pharmaceutics
; 14(7)2022 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890315
3.
Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer.
Clin Transl Sci
; 13(2): 419-429, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31729169
4.
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Cancer Cell
; 33(3): 495-511.e12, 2018 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29502954
5.
Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.
Nat Commun
; 9: 16203, 2018 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29600801
6.
The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.
Nat Commun
; 8: 14797, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28300085
7.
The radiosensitizing effects of Nelfinavir on pancreatic cancer with and without pancreatic stellate cells.
Radiother Oncol
; 119(2): 300-5, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27247056
8.
IP-10/CXCL10 attracts regulatory T cells: Implication for pancreatic cancer.
Oncoimmunology
; 4(9): e1027473, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26405599
9.
KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.
Epigenomics
; 7(4): 609-26, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111032
10.
The stromal compartments in pancreatic cancer: are there any therapeutic targets?
Cancer Lett
; 343(2): 147-55, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24141189
11.
Contextual regulation of pancreatic cancer stem cell phenotype and radioresistance by pancreatic stellate cells.
Radiother Oncol
; 111(2): 243-51, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24780634
12.
IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival.
Oncotarget
; 5(22): 11064-80, 2014 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415223
13.
Pancreatic stellate cells radioprotect pancreatic cancer cells through ß1-integrin signaling.
Cancer Res
; 71(10): 3453-8, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21558392
14.
Breast cancer stem-like cells show dominant homologous recombination due to a larger S-G2 fraction.
Cancer Biol Ther
; 11(12): 1028-35, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21558789