Detalhe da pesquisa
1.
Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice.
Kidney Int
; 94(2): 303-314, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29759420
2.
Polysome shift assay for direct measurement of miRNA inhibition by anti-miRNA drugs.
Nucleic Acids Res
; 44(2): e13, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384419
3.
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).
J Med Chem
; 60(10): 4403-4423, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28471663
4.
Synthesis and characterization of a novel liver-targeted prodrug of cytosine-1-beta-D-arabinofuranoside monophosphate for the treatment of hepatocellular carcinoma.
J Med Chem
; 49(26): 7711-20, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181153
5.
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
J Clin Invest
; 125(1): 141-56, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415439
6.
Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy.
Cell Metab
; 20(4): 626-38, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25295787
7.
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Sci Transl Med
; 4(121): 121ra18, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22344686
8.
A Potent and Selective AMPK Activator That Inhibits de Novo Lipogenesis.
ACS Med Chem Lett
; 1(9): 478-82, 2010 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900234
9.
Delivery of high levels of anti-proliferative nucleoside triphosphates to CYP3A-expressing cells as a potential treatment for hepatocellular carcinoma.
Cancer Chemother Pharmacol
; 64(5): 981-91, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19283354
10.
Liver-targeted drug delivery using HepDirect prodrugs.
J Pharmacol Exp Ther
; 312(2): 554-60, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15340017